Results 81 to 90 of about 4,582 (179)

Carotid body dysregulation contributes to Long COVID symptoms

open access: yesCommunications Medicine
Background The symptoms of long COVID, which include fatigue, breathlessness, dysregulated breathing, and exercise intolerance, have unknown mechanisms.
Ahmed El-Medany   +8 more
doaj   +1 more source

P2X3 receptor antagonism improves hindlimb blood flow during exercise in a conscious ovine model of hypertensive heart failure with preserved ejection fraction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A preclinical large‐animal model of hypertensive heart failure with preserved ejection fraction (HFpEF) was used to examine the role of purinergic P2X3 receptor signalling during treadmill exercise. Animals were instrumented with either thoracic cardiac output and coronary flow probes or abdominal renal and hindlimb blood flow ...
Mridula Pachen   +7 more
wiley   +1 more source

Beyond the Heart‐Lung Axis: A Review of the Crosstalk Between the Hemodynamic, Neurohormonal, and Immune Systems in Pulmonary Hypertension

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega   +4 more
wiley   +1 more source

Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea.

open access: yes, 1999
The chemoreflexes are an important mechanism for regulation of both breathing and autonomic cardiovascular function. Abnormalities in chemoreflex mechanisms may be implicated in increased cardiovascular stress in patients with obstructive sleep apnea ...
Dyken, M E   +5 more
core  

Innovative Dose–Response Assessment of the Metaboreflex With Indirect Control of Intramuscular Metabolic Perturbation in Humans

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim We aimed to evaluate an innovative dose–response approach to assess the metaboreflex with control of intramuscular metabolic perturbation (concept of metaboreflex gain). We also investigated potential sex differences in the metaboreflex using this new approach.
Nabil Kouzkouz   +6 more
wiley   +1 more source

Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation

open access: yesJournal of Neuroinflammation, 2019
Background Lipopolysaccharide (LPS)-induced systemic inflammation (SI) is associated with neuroinflammation in the brain, hypotension, tachycardia, and multiple organs dysfunctions.
Mateus R. Amorim   +8 more
doaj   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

open access: yes
The Journal of Physiology, EarlyView.
Richard J. A. Wilson   +1 more
wiley   +1 more source

Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord‐Injured Humans: A Narrative Review

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three
Rasmus Kopp Hansen   +5 more
wiley   +1 more source

Blockade of NK-1 receptors in the lateral commissural nucleus tractus solitarii of awake rats had no effect on the cardiovascular responses to chemoreflex activation

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The neurotransmission of the chemoreflex in the nucleus tractus solitarii (NTS), particularly of the sympatho-excitatory component, is not completely understood.
C. Zhang, L.G.H. Bonagamba, B.H. Machado
doaj   +1 more source

Postnatal developmental changes in the laryngeal chemosensory cell clusters of rats

open access: yesJournal of Anatomy, Volume 249, Issue 4, Page 769-786, October 2026.
Chemosensory cell clusters appeared in the rat larynx 2 days after birth and were already connected to afferent nerve fibers. Their number increased until 3 weeks of age, then stabilized while continuing to grow through the addition of new cells. Because their number reached a plateau around the time of weaning, their development may be linked to ...
Sayed Sharif Abdali   +5 more
wiley   +1 more source

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