Results 191 to 200 of about 149,400 (379)

Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance [PDF]

, 2006
Sanjay Popat, Richard Wort, Richard S. Houlston   +2 more
openalex   +1 more source

Cisplatin for cancer therapy and overcoming chemoresistance

Heliyon, 2022
R. Ranasinghe, M. Mathai, A. Zulli
semanticscholar   +1 more source

A Network‐Driven Framework for Drug Response Precision Prediction of Acute Myeloid Leukemia

Advanced Science, EarlyView.
A network‐based precision medicine platform, named NetAML is offered for personalized treatment of AML. It combines network analysis and machine learning to develop 87 models predicting drug sensitivity for clinical drugs. NetAML identifies interpretable gene signatures that drive differential drug responses, enabling the prediction of individual ...
Yinyin Wang, Rui Liu, Yinnan Zhang, Xiang Luo, Chengzhuang Yu, Shentong Fang, Ninghua Tan, Jing Tang   +7 more
wiley   +1 more source

Fatty acid receptor GPR120 promotes breast cancer chemoresistance by upregulating ABC transporters expression and fatty acid synthesisResearch in context

EBioMedicine, 2019
Background: Chemoresistance is the major cause of neoadjuvant treatment failure in breast cancer patients. Despite recent progress, the mechanism underlying chemoresistance remains to be further defined.
Xue Wang, Songbing He, Yuting Gu, Qiwei Wang, Xiao Chu, Min Jin, Liang Xu, Qiong Wu, Qianjun Zhou, Bei Wang, Yanyun Zhang, Hui Wang, Leizhen Zheng   +12 more
doaj  

MBD2 regulates the progression and chemoresistance of cholangiocarcinoma through interaction with WDR5

Journal of Experimental & Clinical Cancer Research
Background Cholangiocarcinoma (CCA) is a highly malignant, rapidly progressing tumor of the bile duct. Owing to its chemoresistance, it always has an extremely poor prognosis.
Da Wang, Junsheng Chen, Guanhua Wu, Fei Xiong, Wenzheng Liu, Qi Wang, Yiyang Kuai, Wenhua Huang, Yongqiang Qi, Bing Wang, Ruizhi He, Yongjun Chen   +11 more
doaj   +1 more source

Erratum: Acquired chemoresistance in pancreatic carcinoma cells: induced secretion of IL-1β and NO lead to inactivation of caspases [PDF]

, 2006
Susanne Sebens Müerköster, J Lust, Alexander Arlt, R Häsler, M Witt, T Sebens, S Schreiber, Ulrich R. Fölsch, H. Schäfer   +8 more
openalex   +1 more source

A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155

Advanced Science, EarlyView.
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang, Ting Sun, Si‐tu Xue, Zhong‐di Cai, Hong Yi, Miao Lv, Shi‐bo Kou, Rui Liu, Xiao‐zhong Peng, Zhuo‐rong Li   +9 more
wiley   +1 more source

HOW DOES TOXOPLASMA GONDII MODULATE NEURONAL RESPONSES AND ANTIGEN PRESENTATION TO EVADE IMMUNE RECOGNITION DURING LATENT INFECTION?

IBRO Neuroscience Reports, 2023
Renzo Gutierrez Loli, Amel Aïda, Marcy Belloy, Mohamed Hakimi, Nicolas Blanchard   +4 more
doaj  

DNA-methylation eraser TET2 activates WTIP expression to suppress an AKT-dependent chemoresistance of gastric cancer

Neoplasia: An International Journal for Oncology Research
Chemoresistance is one of the major causes of the failure in gastric cancer (GC) treatment and leads to poor clinical outcomes. Ten-eleven translocation (TET) 2 expression and activity are frequently reduced in solid tumors.
Yan Guo, Hongyang Yu, Jinyang Li, Kewei Liu, Mengyi Han, Yuxin Tang, Li Su, Xianfeng Li, Haixia Wu, Dongfeng Chen   +9 more
doaj  

The prognostic role of VEGF in head and neck squamous cell carcinoma [PDF]

, 2017
Emerging from potentially malignant disorders that in most cases will never become cancerous, head and neck squamous cell carcinoma (HNSCC) is a cancer that is extremely difficult to diagnose early.
Mathew, Rohit Thomas
core