Results 121 to 130 of about 133,222 (232)

A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains

The FEBS Journal, EarlyView.
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley   +1 more source

Enhanced chemotaxis and degradation of nonylphenol in Pseudoxanthomonas mexicana via CRISPR-mediated receptor modification. [PDF]

Sci Rep
Chai R, Guo J, Yang C, Zhu D, Li T, Yang W, Liu X, Chen X, Huang S, Wang H, Yao X, Gao Y, Qiu L.   +12 more
europepmc   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source

The Role of Chemotactic Cytokines in Tick-Borne Encephalitis. [PDF]

Cells
Grygorczuk S, Czupryna P, Martonik D, Parfieniuk-Kowerda A, Adamczuk J, Dunaj-Małyszko J, Giecko M, Osada J, Parczewski M, Flisiak R, Moniuszko-Malinowska A.   +10 more
europepmc   +1 more source

Neutrophils in the Bone Marrow Express DEC205, Guiding Their Migration to Inflamed Tissues

Immunology, EarlyView.
In bone marrow, immature neutrophils express high levels of DEC205, necessary to mediate migration through endothelial cell layers in vitro and in vivo. During maturation and migration to peripheral tissues, expression of DEC205 is downregulated. Thus, expression of DEC205 inversely correlates with the maturation of neutrophils and is involved in ...
Shiying Jin, Xuan Lei, Sonali Singh, Alexander Enk, Karsten Mahnke   +4 more
wiley   +1 more source

Dimensionless Parameters Define Criteria for Optimal Flow Velocity in Enhancing Chemotactic Response toward Residual Contaminants in Porous Media. [PDF]

Environ Sci Technol
Gao B, Ford RM.
europepmc   +1 more source

A Mendelian randomization study on the causal association of circulating cytokines with diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
We performed a two‐sample MR analysis to investigate the causal relationship between circulating cytokines and DN in individuals of European ancestry. We found evidence to support the causal role of genetically predicted circulating levels on the increased risk of DN, including interferon‐gamma, stem cell factor, and stromal‐cell‐derived factor 1 alpha,
Yiming Xu, Tian Xiao, Junqing Yang, Jiali Wang, Bingting Wang, Chen Qiao   +5 more
wiley   +1 more source

Activation of motility and chemotaxis in the spermatozoa. [PDF]

Reprod Med Biol
Yoshida M, Yoshida K.
europepmc   +1 more source

Canagliflozin protects cardiovascular function in type 2 diabetic coronary artery disease by regulating natriuretic peptide B

Journal of Diabetes Investigation, EarlyView.
Canagliflozin regulated the cyclic guanosine monophosphate (cGMP)‐protein kinase 1‐α signaling pathway through the natriuretic peptide B gene, thereby improving cell viability, apoptosis, and reactive oxygen species levels, and ultimately protecting cardiac function in type 2 diabetic patients with coronary artery disease.
Jiarui Zhang, Lichenlu Huang, Yongqin Zheng, Ji Yang, Xiaopei Wu, Jundong He   +5 more
wiley   +1 more source

Pseudomonas aeruginosa Performs Chemotaxis to the Neurotransmitters Serotonin, Dopamine, Epinephrine and Norepinephrine. [PDF]

Microb Biotechnol
Monteagudo-Cascales E, Lozano-Montoya A, Krell T.   +2 more
europepmc   +1 more source