Results 171 to 180 of about 144,701 (323)

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells

open access: green, 2008
Sze‐Kwan Lin   +8 more
openalex   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells.

open access: green, 1991
Carla Zoja   +9 more
openalex   +1 more source

Systemic Effects of Vascular Photobiomodulation on Early Macrophage Recruitment During Skeletal Muscle Repair

open access: yesJournal of Biophotonics, EarlyView.
Preventive vascular photobiomodulation accelerates macrophage recruitment and enhances pro‐regenerative inflammation after skeletal muscle injury, suggesting its potential to improve tissue repair through timely modulation of the immune response. ABSTRACT Muscle injuries involve a complex inflammatory response in which macrophages are essential for ...
Raquel Lira Ortiz da Silva   +8 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

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