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Neutrophil chemotactic factors in asthma.
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The influence of chemotactic factors on neutrophil adhesiveness
Inflammation, 1978The ability of several chemotactic factors to alter polymorphonuclear neutrophil (PMN) adhesiveness to nylon fibers was studied. Partly purified bacterial chemotactic factor, the isolated chemotactic fragment of human C5, and the chemotactic synthetic tripeptide, formyl-methionyl-leucyl-phenylalanine, transiently enhanced the nylon fiber adhesiveness ...
J T O'Flaherty +2 more
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Pertussis toxin inhibition of chemotactic factor-induced calcium mobilization and function in human polymorphonuclear leukocytes. [PDF]
Chemotactic factors stimulate a rapid increase in the cytosolic concentration of intracellular calcium ions ([Ca2+]in) in human polymorphonuclear leukocytes (PMNL), which may be an event that is critical to the expression of chemotaxis and other PMNL ...
D W Goldman, F H Chang, H R Bourne
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Chemotactic factors for bovine leukocytes
American Journal of Veterinary Research, 1982SUMMARY An agarose method was used to determine the nature of chemotaxins for bovine leukocytes as related to coliform mastitis. Freshly collected bovine serum or plasma was frequently chemotactic, probably due to spontaneous complement activation. Fresh serum was always rendered chemotactic when activated with zymosan or when heat-killed or viable ...
E J, Carroll, R, Mueller, L, Panico
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Chemotactic factors and renal inflammation
American Journal of Kidney Diseases, 1998The mechanisms of leukocyte entry into the kidney during inflammatory renal disease have recently received considerable attention. Chemotactic factors appear to play a central role in this process, not only by inducing leukocyte movement but also by enhancing endothelial and leukocyte adhesiveness and endothelial permeability.
B H, Rovin, L T, Phan
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Are Growth Factors Chemotactic Agents?
Experimental Cell Research, 1995We report the first direct observation of chemotaxis in slowly moving malignant cells. Two sarcoma cell lines of different metastatic potential were used. In a direct-viewing chemotaxis chamber with two concentric wells, the pooled trajectories of highly malignant rat T15 cells were strongly biased toward the outer well which contained platelet-derived
D, Zicha, G A, Dunn
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International Archives of Allergy and Applied Immunology, 2009
An eosinophil chemotactic factor (ECF) can be released from human polymorphonuclear neutrophils by arachidonic acid (AA), its methyl ester, but not by other derivatives such as AA ethyl ester and arachidonyl acetate. The ECF is highly specific for eosinophils and does not attract polymorphonuclear neutrophils. A dose-dependent non-cytotoxic ECF release
H. Tesch, W. König, N. Frickhofen
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An eosinophil chemotactic factor (ECF) can be released from human polymorphonuclear neutrophils by arachidonic acid (AA), its methyl ester, but not by other derivatives such as AA ethyl ester and arachidonyl acetate. The ECF is highly specific for eosinophils and does not attract polymorphonuclear neutrophils. A dose-dependent non-cytotoxic ECF release
H. Tesch, W. König, N. Frickhofen
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Neutrophil chemotactic factors
1991Polymorphonuclear leukocytes (neutrophils) are recruited to inflammatory sites by a variety of soluble mediators (chemoattractants) that stimulate neutrophil directed migration (chemotaxis). Many neutrophil chemoattractants such as neutrophil activating proteins, leukotriene B4 (LTB4), platelet activating factor, and complement-derived C5a, are ...
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