Results 121 to 130 of about 303,315 (362)

Adaptation kinetics in bacterial chemotaxis [PDF]

open access: yes, 1983
Cells of Escherichia coli, tethered to glass by a single flagellum, were subjected to constant flow of a medium containing the attractant alpha-methyl-DL-aspartate. The concentration of this chemical was varied with a programmable mixing apparatus over a
Berg, Howard C.   +2 more
core   +1 more source

Locally excitable Cdc42 signals steer cells during chemotaxis

open access: yesNature Cell Biology, 2015
Neutrophils and other amoeboid cells chemotax by steering their front ends towards chemoattractant. Although Ras, Rac, Cdc42 and RhoA small GTPases all regulate chemotaxis, it has been unclear how they spatiotemporally control polarization and steering ...
Heebum Yang, Sean R. Collins, T. Meyer
semanticscholar   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

open access: yesAdvanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen   +2 more
wiley   +1 more source

Novel Pseudotaxis Mechanisms Improve Migration of Straight-Swimming Bacterial Mutants Through a Porous Environment

open access: yesmBio, 2015
Bacterial locomotion driven by flagella is given directionality by the chemotaxis signal transduction network. In the classic plate assays of migration in porous motility agar, efficient motility is compromised in chemotaxis mutants of diverse bacteria ...
Bitan Mohari   +7 more
doaj   +1 more source

Bacterial chemotaxis without gradient-sensing [PDF]

open access: yes, 2013
Models for chemotaxis are based on gradient sensing of individual organisms. The key contribution of Keller and Segel is showing that erratic movements of individuals may result in an accurate chemotaxis phenomenon as a group.
Kim, Yong-Jung, Yoon, Changwook
core  

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

open access: yesAdvanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi   +5 more
wiley   +1 more source

Analysis of a chemotaxis system modeling ant foraging

open access: yes, 2015
In this paper we analyze a system of PDEs recently introduced in [P. Amorim, {\it Modeling ant foraging: a {chemotaxis} approach with pheromones and trail formation}], in order to describe the dynamics of ant foraging.
Alonso, Ricardo   +2 more
core   +2 more sources

Bacterial‐Based Molecular Communication: Simulation of a Fixed and Receding Receiver Scenarios in Varied Viscosities and Environmental Conditions

open access: yesAdvanced Theory and Simulations, EarlyView.
This study presents a robust 3D simulation for BBMC, focusing on both fixed and receding receiver scenarios across various conditions. Key parameters such as D, Q, u, and d are tested at different values to assess the performance and reliability of BBMC in applications like drug delivery, addressing critical challenges in nanoscale communication with ...
Mustafa Ozan Duman   +3 more
wiley   +1 more source

Relation between chemotaxis and consumption of amino acids in bacteria

open access: yesMolecular Microbiology, 2015
Chemotaxis enables bacteria to navigate chemical gradients in their environment, accumulating toward high concentrations of attractants and avoiding high concentrations of repellents.
Yiling Yang   +6 more
semanticscholar   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang   +8 more
wiley   +1 more source

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