Results 131 to 140 of about 404,279 (303)

Über die Beteiligung der Chemotaxis bei pathologischen Vorgängen

, 1914
Theodor Leber
openalex   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling

, 2006
Silvia Rossi Paccani, Fiorella Tonello, Laura Patrussi, Nagaja Capitani, Morena Simonato, Cesare Montecucco, Cosima T. Baldari   +6 more
openalex   +2 more sources

Chemotaxis ofEntamoeba histolyticatowards the pro-inflammatory cytokine TNF is based on PI3K signalling, cytoskeleton reorganization and the GalactoseN-acetylgalactosamine lectin activity [PDF]

, 2008
Samantha Blazquez, Ghislaine Guigon, Christian Weber, Sylvie Syan, Odile Sismeiro, Jean-Yves Coppe, Elisabeth Labruyre, Nancy Guilln   +7 more
openalex   +1 more source

Iron/Cobalt Dual‐Atom Catalyst Orchestrate Photothermal‐Chemodynamic Immunotherapy Against MRSA: Multi‐Omics Dissection in Murine and Porcine Models

Advanced Science, EarlyView.
FeCo dual‐atom catalyst (FeCo‐N‐DAC) with ultrahigh metal loading (Fe > 5.4%, Co > 4.8%) is developed for synergistic photothermal‐chemodynamic immunotherapy. FeCo‐N‐DAC penetrates deep‐seated tissues, eradicates MRSA biofilms, and reprograms immune‐inflammatory pathways via multi‐omics‐validated mechanisms.
Shihao Xu, Binge Huang, Hao Lin, Jinming Li, Zhaoxiang Lu, Qi Zhang, Jia Li, Shiping Yang, Songsong Lan, Yan Yang, Yun Feng, Xiaojun He   +11 more
wiley   +1 more source

Experimental evolution partially restores functionality of bacterial chemotaxis network with reduced number of components.

PLoS Genetics
The chemotaxis signaling pathway, which enables bacteria to follow chemical gradients in their environment, is highly conserved among motile bacteria. It is assumed that Escherichia coli contains the minimal and non-redundant set of protein activities ...
Manika Kargeti, Irina Kalita, Sarah Hoch, Maryia Ratnikava, Wenhao Xu, Bin Ni, Ron L Dy, Remy Colin, Victor Sourjik   +8 more
doaj   +1 more source

Boundedness and asymptotic behavior in a quasilinear two-species chemotaxis system with loop

, 2023
Chao Liu, Bin Liu
openalex   +2 more sources

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

High red/far-red ratio promotes root colonization of Serratia plymuthica A21-4 in tomato by root exudates-stimulated chemotaxis and biofilm formation [PDF]

, 2023
Zhixin Guo, Yanping Qin, Jingli Lv, Xiaojie Wang, Ting Ye, Xiaoxing Dong, Nanshan Du, Tao Zhang, Fengzhi Piao, Han Dong, Shunshan Shen   +10 more
openalex   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source