Results 261 to 270 of about 277,155 (334)

Watching axons on the move. [PDF]

Elife
Lazaro-Pena MI, Diaz-Balzac CA.
europepmc   +1 more source

Neuroprotective Potential of the Flavonoids Quercetin and Epicatechin in a C. elegans Tauopathy Model

Molecular Nutrition &Food Research, EarlyView.
Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García, Begoña Ayuda‐Durán, Susana González‐Manzano, Celestino Santos‐Buelga, Ana M. González‐Paramás   +4 more
wiley   +1 more source

Shielding Human Adipocytes From Inflammation: The Protective Potential of Polyphenol‐Rich Opuntia ficus‐indica Cladode Extract

Molecular Nutrition &Food Research, EarlyView.
Inflammation of the adipose tissue contributes to metabolic disorders. OFI‐CE regulates the expression of proinflammatory genes in human hypertrophic fat cells. OFI‐CE is a promising candidate for use as a dietary supplement or therapeutic agent in nutritional interventions targeting inflammatory markers associated with obesity.
Stefano Quarta, Nadia Calabriso, Maria Annunziata Carluccio, Clara Albano, Ibrahim Khalifa, Martin Wabitsch, Federica Blando, Marika Massaro   +7 more
wiley   +1 more source

FMO2⁺ cancer-associated fibroblasts sensitize anti-PD-1 therapy in patients with hepatocellular carcinoma. [PDF]

J Immunother Cancer
Xu W, Weng J, Zhao Y, Xie P, Xu M, Liu S, Yu Q, Yu M, Liang B, Chen J, Sun HC, Li H, Ye Q, Shen Y.   +13 more
europepmc   +1 more source

Mitochondrial Fusion Protein 2‐Modified Bone Marrow Mesenchymal Stem Cells Improved Hyperglycemia‐Induced Schwann Cell Injury via Regulating Mitochondria‐Associated Endoplasmic Reticulum Membranes

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective High glucose damages rat Schwann cells (SCs), which is closely related to the dysfunction of mitochondria‐associated endoplasmic reticulum membranes (MAMs). Therefore, the present study aimed to investigate the protective effects and mechanisms of modified bone marrow mesenchymal stem cells (BMSCs) and mitochondrial fusion protein 2 (
Housheng Fu, Zhewen Ou, Fei Wang, Weifu Wang, Zhongyao Wang   +4 more
wiley   +1 more source

Activation of motility and chemotaxis in the spermatozoa. [PDF]

Reprod Med Biol
Yoshida M, Yoshida K.
europepmc   +1 more source

Atomically Precise Nanoclusters as Co‐Catalysts for Light‐Activated Microswimmer Motility

Small, EarlyView.
For the first time, atomically precise gold nanoclusters (AuNCs) are used as motility catalysts for active matter microswimmers. The nanoscale precision and controlled optical activity of AuNCs are leveraged, achieving a nearly fivefold increase in displacement under ultraviolet light compared to prototypical TiO2 microswimmers.
John Castañeda, Blake Rogers, Ysaris Sosa, Jorge A. Muñoz, Badri Bhattarai, Ashley M. Martinez, M. Lisa Phipps, Demosthenes P. Morales, Matthew N. Montoya Rush, Miguel José Yacaman, Gabriel A. Montaño, John G. Gibbs, Jennifer S. Martinez   +12 more
wiley   +1 more source

Characterizing the Role of <i>Moringa oleifera</i> Lam (MO) Leaves and Root Extracts on <i>Dictyostelium discoideum</i> Cell Behavior. [PDF]

Biology (Basel)
Alamer SA, Sherif FE.
europepmc   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
wiley   +1 more source

Fusobacterium nucleatum promotes anastomotic leakage by activating epithelial cells through the NOD1/RIPK2/ERK signalling pathway to drive IL-1β-induced neutrophil chemotaxis and collagen degradation. [PDF]

Clin Transl Med
Wei Z, Bao L, Li B, Yang J, Wang J, Xu F, Wenren H, Zhang K, Shi S, Yan L, Tao X, Zhang T, Wang Z, Liu Y.   +13 more
europepmc   +1 more source