Results 121 to 130 of about 2,538,615 (320)

Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non–Small Cell Lung Cancer

JAMA Oncology, 2020
Key Points Question Does first-line durvalumab treatment with or without tremelimumab improve survival outcomes vs chemotherapy in patients with metastatic non–small cell lung cancer?
N. Rizvi, B. Cho, N. Reinmuth, K. Lee, A. Luft, M. Ahn, M. M. van den Heuvel, M. Cobo, D. Vicente, A. Smolin, V. Moiseyenko, S. Antonia, S. Le Moulec, G. Robinet, R. Natale, J. Schneider, F. Shepherd, Sarayut Lucien Geater, E. Garon, Edward S. Kim, S. Goldberg, K. Nakagawa, R. Raja, B. Higgs, A. Boothman, Luping Zhao, U. Scheuring, P. Stockman, V. Chand, S. Peters   +29 more
semanticscholar   +1 more source

Preoperative elevation of serum C-reactive protein as an indicator of poor prognosis for early-stage esophageal squamous cell carcinoma

Kaohsiung Journal of Medical Sciences, 2013
Preoperative elevation of serum C-reactive protein (CRP) is reportedly associated with poor prognosis in several types of cancer. This study investigated the role of serum CRP as a prognostic factor in early-stage esophageal squamous cell carcinoma (ESCC)
Zheng-Bo Song, Bao-Chai Lin, Bo Li, Chun-Xiao He, Bei-Bei Zhang, Lan Shao, Yi-Ping Zhang   +6 more
doaj   +1 more source

Model for tumour growth with treatment by continuous and pulsed chemotherapy [PDF]

arXiv, 2013
In this work we investigate a mathematical model describing tumour growth under a treatment by chemotherapy that incorporates time-delay related to the conversion from resting to hunting cells. We study the model using values for the parameters according to experimental results and vary some parameters relevant to the treatment of cancer.
arxiv  

The Increased Incidence of Nausea and Vomiting Due to Anxiety in Paclitaxel Carboplatin Chemotherapy in a 48 Years Old Female Patient with Cervical Cancer: a Case Report [PDF]

, 2014
Nausea and vomiting was the frequently side effects in chemotherapy.Uncontrolled nausea and vomiting can cause weakened body condition, reduced appetite and drinking, dehydration, electrolyte disturbances, reduced nutritional status so the patient ...
Noviyani, R. (R), Putra, I. F. (I), Suwiyoga, and, K   +2 more
core  

The next steps in improving the outcomes of advanced ovarian cancer [PDF]

, 2015
Worldwide ovarian cancer affects over 200,000 women per year. Overall survival rates are poor due to two predominate reasons. First, the majority of patients present with advanced disease creating significant difficulty with effecting disease eradication.
Blagden, S, Fotopoulou, C, Gabra, H, Openshaw, MR   +3 more
core   +1 more source

Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation

Scientific Reports, 2017
Podoplanin/Aggrus, known as a platelet aggregation-inducing factor, is frequently overexpressed in lung squamous cell carcinomas (LSCC) and glioblastomas among other tumours, and its expression has been reported to be correlated with poor prognosis ...
Kenichi Miyata, Ai Takemoto, Sakae Okumura, Makoto Nishio, Naoya Fujita   +4 more
doaj   +1 more source

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

New England Journal of Medicine, 2018
BACKGROUND Treatment of newly diagnosed advanced‐stage ovarian cancer typically involves cytoreductive surgery and systemic chemotherapy. We conducted a trial to investigate whether the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to ...
W. V. van Driel, S. Koole, K. Sikorska, J. H. Schagen van Leeuwen, H. Schreuder, R. Hermans, I. D. de Hingh, J. van der Velden, H. Arts, L. Massuger, A. Aalbers, V. Verwaal, J. Kieffer, Koen K. van de Vijver, H. van Tinteren, N. Aaronson, G. Sonke   +16 more
semanticscholar   +1 more source

Repurposing Metformin: Potential as a Prevention, Treatment and Adjunct Therapy in Pancreatic Cancer

Quality in Sport
Metformin, a widely prescribed treatment for type II diabetes, offers promising benefits beyond glycemic control, including improved lipid profiles and cardiovascular outcomes.
Emilia Kamizela, Anna Rudzińska, Kacper Ponikowski, Kacper Wrzosek, Paulina Gumółka, Jakub Oberda, Alicja Paluch, Sylwia Haba, Karol Jakubik, Eliza Kolasa, Katarzyna Szklener   +10 more
doaj   +1 more source

Antibiotic dosing in obesity: size does matter? [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Currently, from 15 to 50% of the population in the developed countries has obesity. Overall, patients with obesity have a higher risk of infection; they are more likely to develop infectious complications after surgical interventions and have a higher ...
Andreeva I.V., Stetsiouk O.U., Kozlov R.S.   +2 more
doaj  

Modelling chemotherapy resistance in palliation and failed cure [PDF]

, 2009
The goal of palliative cancer chemotherapy treatment is to prolong survival and improve quality of life when tumour eradication is not feasible. Chemotherapy protocol design is considered in this context using a simple, robust, model of advanced tumour ...
Aabo, Becker, Bello, Bertolini, Browder, Brünner, Citron, Citron, De Placido, Eamonn A. Gaffney, Fallik, Gaffney, Gaffney, Goldie, Goldie, Gompertz, Gorczyca, Hahnfeldt, Hall, Helen C. Monro, Jaffrezou, Kerbel, Laird, Law, Liu, Looney, Luria, Man, Midgley, Midgley, Midgley, Norton, Norton, Norton, Norton, Norton, Piccart, Piccart-Gebhart, Rew, Sieber, Simon, Simpson-Herren, Siodlak, Sullivan, Summer, Tiffany, Vasey, Wickramanayake, Winsor   +48 more
core   +3 more sources