Results 171 to 180 of about 2,538,615 (320)

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

open access: yes, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena   +4 more
core   +1 more source

A Dual Approach for Positive T-S Fuzzy Controller Design and Its Application to Cancer Treatment Under Immunotherapy and Chemotherapy [PDF]

open access: yesarXiv, 2019
This study proposes an effective positive control design strategy for cancer treatment by resorting to the combination of immunotherapy and chemotherapy. The treatment objective is to transfer the initial number of tumor cells and immune-competent cells from the malignant region into the region of benign growth where the immune system can inhibit tumor
arxiv  

The dose-dense principle in chemotherapy [PDF]

open access: yesarXiv, 2017
Chemotherapy is a class of cancer treatment that uses drugs to kill cancer cells. A typical chemotherapeutic protocol consists of several drugs delivered in cycles of three weeks. We present mathematical analyses demonstrating the existence of a maximum time between cycles of chemotherapy for a protocol to be effective.
arxiv  

Simulation of mass transport during intraperitoneal chemotherapy : a parametrical model of single tumor nodules [PDF]

open access: yes, 2016
OBJECTIVES Patients with peritoneal carcinomatosis suffer from a widespread metastatic growth of tumor nodules in the peritoneal cavity. Although Intraperitoneal (IP) chemotherapy allows for higher intratumor concentrations of the cytotoxic agent ...
Ceelen, Wim   +4 more
core  

The development of drug resistance in metastatic tumours under chemotherapy: an evolutionary perspective [PDF]

open access: yesarXiv
We present a mathematical model of the evolutionary dynamics of a metastatic tumour under chemotherapy, comprising non-local partial differential equations for the phenotype-structured cell populations in the primary tumour and its metastasis. These equations are coupled with a physiologically-based pharmacokinetic model of drug delivery, implementing ...
arxiv  

Discussion on Chemotherapy in Malignant Disease [PDF]

open access: bronze, 1948
Alexander Haddow, Edith Paterson
openalex   +1 more source

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