BACKGROUND The survival of patients with diffuse large-B-cell lymphoma after chemotherapy is influenced by molecular features of the tumors. We used the gene-expression profiles of these lymphomas to develop a molecular predictor of survival.
A. Rosenwald+39 more
semanticscholar +1 more source
Ceftazidimeavibactam use in children and adolescents [PDF]
The increasing number of infections caused by multidrug-resistant gram-negative bacteria in children is a serious problem all over the world. Ceftazidim-avibactam is a promising antimicrobial drug recently approved in Russia for use in pediatric practice.
Stetsiouk О.U.+3 more
doaj +1 more source
Mechanisms of Multidrug Resistance in Cancer Chemotherapy
Cancer is one of the main causes of death worldwide. Despite the significant development of methods of cancer healing during the past decades, chemotherapy still remains the main method for cancer treatment. Depending on the mechanism of action, commonly
K. Bukowski, M. Kciuk, R. Kontek
semanticscholar +1 more source
21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer.
BACKGROUND The recurrence score based on the 21-gene breast-cancer assay has been clinically useful in predicting a chemotherapy benefit in hormone-receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, axillary lymph-node-negative ...
K. Kalinsky+33 more
semanticscholar +1 more source
Oral third-generation cephalosporins in the treatment of community-acquired urinary tract infections [PDF]
Cephalosporins are one of the most commonly used antimicrobials for the treatment of variety of bacterial infections. Prudent use of the third-generation cephalosporins is important for the control of spread of cephalosporin-resistant Gram-negative ...
Kozlov R.S., Palagin I.S., Golub A.V.
doaj +1 more source
Background: Acinetobacter species other than A. baumannii are becoming increasingly more important as opportunistic pathogens for humans. The primary aim of this study was to assess the prevalence, species distribution, antimicrobial resistance patterns,
Eugene Sheck+13 more
doaj +1 more source
In vitro activity of macrolides against Streptococcus pneumoniae and Streptococcus pyogenes in the Russian Federation: “Status praesens” [PDF]
Objective. To evaluate in vitro activity of various macrolide antibiotics against a current collection of clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes isolated from patients with community-acquired infections in different ...
Kozlov R.S.+3 more
doaj +1 more source
A Retrospective Data Analysis of the Structure of Isolated Microorganisms in Secondary Skin and Soft Tissue Infections Using Permuted Test [PDF]
Objective. Objectives. To analyze the structure of microorganisms isolated in patients with secondary skin and soft tissues infection (SSTIs) (trophic ulcers in patients with diabetes mellitus (DM), chronic arterial insufficiency (CAI), chronic venous ...
Kuzmenkov A.Yu.+5 more
doaj
First experience of using Brentuximab vedotin and modified program NHL-BFM-90 in the front-line treatment of patient with anaplastic large-cell lymphoma: a case report and a review of literature [PDF]
Nodal anaplastic ALK-negative large cell lymphoma (nALCL, ALK-) is a Т-cell lymphoma that is characterized by aggressive clinical course and low sensitivity to СНОР (cyclophosphamide, doxorubicin, vincristine, prednisolone) and other chemotherapy regimen.
N G CHERNOVA+10 more
doaj +1 more source
Nasopharyngeal carriage of Streptococcus pneumoniae in children from day-care centers in Smolensk [PDF]
Objective. To investigate a nasopharyngeal carriage and serotypes of S. pneumoniae in children aged 3 to 6 years from day-care centers in Smolensk. Materials and Methods. A total of 245 isolates of S.
Zharkova L.P.+3 more
doaj +1 more source