Journal of Clinical Oncology, 2021 PURPOSE We report the first 5-year follow-up of any first-line phase III immunotherapy trial for non–small-cell lung cancer (NSCLC). KEYNOTE-024 (ClinicalTrials.gov identifier: NCT02142738) is an open-label, randomized controlled trial of pembrolizumab ...
M. Reck +18 more
semanticscholar +1 more source
Candidate genes in gastric cancer identified by constructing a weighted gene co-expression network [PDF]
PeerJ, 2018 Background Gastric cancer (GC) is one of the most common cancers with high mortality globally. However, the molecular mechanisms of GC are unclear, and the prognosis of GC is poor.
Jian Chen +5 more
doaj +2 more sources
Induction chemotherapy in the treatment of nasopharyngeal carcinoma: Clinical outcomes and patterns of care [PDF]
, 2018 The role of induction chemotherapy in nasopharyngeal carcinoma (NPC) remains controversial. The primary aim of this study was to use the National Cancer Database to evaluate the patterns of care of induction chemotherapy in NPC and its impact on overall ...
Adkins, Douglas +10 more
core +2 more sources
Ceftazidimeavibactam use in children and adolescents [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2021 The increasing number of infections caused by multidrug-resistant gram-negative bacteria in children is a serious problem all over the world. Ceftazidim-avibactam is a promising antimicrobial drug recently approved in Russia for use in pediatric practice.
Stetsiouk О.U. +3 more
doaj +1 more source
Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]
, 2003 Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Brinkbäumer, K. +6 more
core +1 more source
Increased survival with enzalutamide in prostate cancer after chemotherapy.
New England Journal of Medicine, 2012 BACKGROUND Enzalutamide (formerly called MDV3100) targets multiple steps in the androgen-receptor-signaling pathway, the major driver of prostate-cancer growth.
H. Scher +19 more
semanticscholar +1 more source
Oral third-generation cephalosporins in the treatment of community-acquired urinary tract infections [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2019 Cephalosporins are one of the most commonly used antimicrobials for the treatment of variety of bacterial infections. Prudent use of the third-generation cephalosporins is important for the control of spread of cephalosporin-resistant Gram-negative ...
Kozlov R.S., Palagin I.S., Golub A.V.
doaj +1 more source
The known-unknown: third- and fourth-generation cephalosporins combined with sulbactam [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 Despite the presence of more than 100 different antibacterials in the therapeutic arsenal, beta-lactam antibiotics, in general, and the third-generation cephalosporins, in particular, remain the main option for the treatment of the most of infections in ...
Stetsiouk O.U. +3 more
doaj +1 more source
A Retrospective Analysis using Deep-Learning Models for Prediction of Survival Outcome and Benefit of Adjuvant Chemotherapy in Stage II/III Colorectal Cancer [PDF]
arXiv, 2021 Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately predict survival benefit from postoperative chemotherapy.
arxiv