Results 51 to 60 of about 2,538,615 (320)

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer.

New England Journal of Medicine, 2005
BACKGROUND We present the combined results of two trials that compared adjuvant chemotherapy with or without concurrent trastuzumab in women with surgically removed HER2-positive breast cancer.
E. Romond, E. Perez, J. Bryant, V. Suman, C. Geyer, N. Davidson, E. Tan-chiu, S. Martino, S. Paik, P. Kaufman, S. Swain, T. Pisansky, L. Fehrenbacher, L. Kutteh, V. Vogel, D. Visscher, G. Yothers, R. Jenkins, A. Brown, S. Dakhil, E. Mamounas, W. Lingle, P. Klein, J. Ingle, N. Wolmark   +24 more
semanticscholar   +1 more source

21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer.

New England Journal of Medicine, 2021
BACKGROUND The recurrence score based on the 21-gene breast-cancer assay has been clinically useful in predicting a chemotherapy benefit in hormone-receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, axillary lymph-node-negative ...
K. Kalinsky, W. Barlow, J. Gralow, F. Meric-Bernstam, K. Albain, D. Hayes, N. Lin, E. A. Perez, L. Goldstein, S. Chia, S. Dhesy-Thind, Priya Rastogi, E. Alba, S. Delaloge, Miguel Martín, C. Kelly, M. Ruíz-Borrego, M. Gil-Gil, C. Arce‐Salinas, E. Brain, Eun-Sook Lee, J. Pierga, B. Bermejo, Manuel Ramos-Vázquez, K. Jung, J. Ferrero, A. Schott, S. Shak, Priyanka Sharma, D. Lew, Jieling Miao, D. Tripathy, L. Pusztai, G. Hortobagyi   +33 more
semanticscholar   +1 more source

A Retrospective Data Analysis of the Structure of Isolated Microorganisms in Secondary Skin and Soft Tissue Infections Using Permuted Test [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2016
Objective. Objectives. To analyze the structure of microorganisms isolated in patients with secondary skin and soft tissues infection (SSTIs) (trophic ulcers in patients with diabetes mellitus (DM), chronic arterial insufficiency (CAI), chronic venous ...
Kuzmenkov A.Yu., Trushin I.V., Mladov V.V., Makushkin B.B., Narezkin D.V., Kozlov R.S.   +5 more
doaj  

In vitro activity of macrolides against Streptococcus pneumoniae and Streptococcus pyogenes in the Russian Federation: “Status praesens” [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. To evaluate in vitro activity of various macrolide antibiotics against a current collection of clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes isolated from patients with community-acquired infections in different ...
Kozlov R.S., Ivanchik N.V., Mikotina A.V., Dekhnich A.V.   +3 more
doaj   +1 more source

First experience of using Brentuximab vedotin and modified program NHL-BFM-90 in the front-line treatment of patient with anaplastic large-cell lymphoma: a case report and a review of literature [PDF]

Терапевтический архив, 2018
Nodal anaplastic ALK-negative large cell lymphoma (nALCL, ALK-) is a Т-cell lymphoma that is characterized by aggressive clinical course and low sensitivity to СНОР (cyclophosphamide, doxorubicin, vincristine, prednisolone) and other chemotherapy regimen.
N G CHERNOVA, E E ZVONKOV, D S BADMAZHAPOVA, M N SINITSYNA, L A GREBENYUK, Y V SIDOROVA, I E KOSTINA, A M KOVRIGINA, T N OBUKHOVA, A B SUDARIKOV, V G SAVCHENKO   +10 more
doaj   +1 more source

Nasopharyngeal carriage of Streptococcus pneumoniae in children from day-care centers in Smolensk [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2020
Objective. To investigate a nasopharyngeal carriage and serotypes of S. pneumoniae in children aged 3 to 6 years from day-care centers in Smolensk. Materials and Methods. A total of 245 isolates of S.
Zharkova L.P., Krechikova O.I., Chagaryan A.N., Kozlov R.S.   +3 more
doaj   +1 more source

Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer.

New England Journal of Medicine, 2002
BACKGROUND We conducted a randomized study to determine whether any of three chemotherapy regimens was superior to cisplatin and paclitaxel in patients with advanced non-small-cell lung cancer.
J. Schiller, D. Harrington, C. Belani, C. Langer, A. Sandler, J. Krook, Junming Zhu, David H. Johnson   +7 more
semanticscholar   +1 more source

Effect of Camrelizumab vs Placebo Added to Chemotherapy on Survival and Progression-Free Survival in Patients With Advanced or Metastatic Esophageal Squamous Cell Carcinoma: The ESCORT-1st Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Standard first-line therapy for advanced or metastatic esophageal carcinoma is chemotherapy, but the prognosis remains poor. Camrelizumab (an anti-programmed death receptor 1 [PD-1] antibody) showed antitumor activity in previously treated ...
Hui‐yan Luo, J. Lu, Y. Bai, T. Mao, Jun Wang, Q. Fan, Yiping Zhang, K. Zhao, Zhendong Chen, Shegan Gao, Jiancheng Li, Z. Fu, K. Gu, Zhihua Liu, Lin Wu, Xiaodong Zhang, Jifeng Feng, Z. Niu, Y. Ba, He-long Zhang, Ying Liu, Li Zhang, Xuhong Min, Jing Huang, Ying Cheng, Dong Wang, Yuzhen Shen, Qing Yang, J. Zou, Rui-Hua Xu   +29 more
semanticscholar   +1 more source

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

New England Journal of Medicine, 2001
BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30 percent of breast cancers, increasing the aggressiveness of the tumor.
D. Slamon, B. Leyland-Jones, Steven Shak, Hank Fuchs, Virginia Paton, A. Bajamonde, Thomas R. Fleming, W. Eiermann, Janet Wolter, M. Pegram, J. Baselga, Larry Norton   +11 more
semanticscholar   +1 more source

A Decision Making Approach for Chemotherapy Planning based on Evolutionary Processing [PDF]

arXiv, 2023
The problem of chemotherapy treatment optimization can be defined in order to minimize the size of the tumor without endangering the patient's health; therefore, chemotherapy requires to achieve a number of objectives, simultaneously. For this reason, the optimization problem turns to a multi-objective problem.
arxiv