Results 51 to 60 of about 2,840,126 (395)

In vitro culture with gemcitabine augments death receptor and NKG2D ligand expression on tumour cells [PDF]

, 2019
Much effort has been made to try to understand the relationship between chemotherapeutic treatment of cancer and the immune system. Whereas much of that focus has been on the direct effect of chemotherapy drugs on immune cells and the release of antigens
A Ashkenazi, A Cerwenka, A Hadji, A Orbach, AP Costa-Pereira, Baryshnikov AYu, C Fionda, H Cho, HA Elrod, I Viard-Leveugle, J Sträter, J Wu, JC Symes, K Yamamoto, L Boldrini, L Galligan, L Siena, M Christgen, M Mottolese, M Müller, M Todaro, M Villa-Morales, MA Park, ME Peter, N Gordon, O Micheau, PB Carvalho-Neto de, RW McGilvray, S Yang, V Almendro, WM Liu, Y Hirooka, Y Kimura   +32 more
core   +2 more sources

BEV-IP : perioperative chemotherapy with bevacizumab in patients undergoing cytoreduction and intraperitoneal chemoperfusion for colorectal carcinomatosis [PDF]

, 2015
Background: Selected patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) benefit from cytoreductive surgery (CRS) combined with intraperitoneal chemoperfusion (IPC).
Ceelen, Wim, Liberale, Gabriel, Van Der Speeten, Kurt, Willaert, Wouter   +3 more
core   +2 more sources

Effect of Camrelizumab vs Placebo Added to Chemotherapy on Survival and Progression-Free Survival in Patients With Advanced or Metastatic Esophageal Squamous Cell Carcinoma: The ESCORT-1st Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Standard first-line therapy for advanced or metastatic esophageal carcinoma is chemotherapy, but the prognosis remains poor. Camrelizumab (an anti-programmed death receptor 1 [PD-1] antibody) showed antitumor activity in previously treated ...
Hui‐yan Luo, J. Lu, Y. Bai, T. Mao, Jun Wang, Q. Fan, Yiping Zhang, K. Zhao, Zhendong Chen, Shegan Gao, Jiancheng Li, Z. Fu, K. Gu, Zhihua Liu, Lin Wu, Xiaodong Zhang, Jifeng Feng, Z. Niu, Y. Ba, He-long Zhang, Ying Liu, Li Zhang, X. Min, Jing Huang, Ying Cheng, Dong Wang, Yuzhen Shen, Qing Yang, J. Zou, Rui-Hua Xu   +29 more
semanticscholar   +1 more source

Antimicrobial resistance of nosocomial Enterobacteriaceae isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 1670 isolates of Enterobacteriaceae collected in 35 hospitals of 22 cities of Russia
Sukhorukova M.V., Edelstein M.V., Skleenova E.Yu., Ivanchik N.V., Mikotina A.V., Dekhnich A.V., Kozlov R.S., «MARATHON» Study Group   +7 more
doaj  

First experience of using Brentuximab vedotin and modified program NHL-BFM-90 in the front-line treatment of patient with anaplastic large-cell lymphoma: a case report and a review of literature [PDF]

Терапевтический архив, 2018
Nodal anaplastic ALK-negative large cell lymphoma (nALCL, ALK-) is a Т-cell lymphoma that is characterized by aggressive clinical course and low sensitivity to СНОР (cyclophosphamide, doxorubicin, vincristine, prednisolone) and other chemotherapy regimen.
N G CHERNOVA, E E ZVONKOV, D S BADMAZHAPOVA, M N SINITSYNA, L A GREBENYUK, Y V SIDOROVA, I E KOSTINA, A M KOVRIGINA, T N OBUKHOVA, A B SUDARIKOV, V G SAVCHENKO   +10 more
doaj   +1 more source

Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up. [PDF]

, 2019
BackgroundNovel second-line treatments are needed for patients with advanced urothelial cancer (UC). Interim analysis of the phase III KEYNOTE-045 study showed a superior overall survival (OS) benefit of pembrolizumab, a programmed death 1 inhibitor ...
Bajorin, DF, Bellmunt, J, Choueiri, TK, Climent, MA, Culine, S, de Wit, R, Fong, L, Fradet, Y, Frenkl, TL, Gerritsen, W, Gurney, H, Lee, JL, Nam, K, Necchi, A, Perini, RF, Petrylak, DP, Quinn, DI, Sternberg, CN, Vaughn, DJ, Vogelzang, NJ   +19 more
core   +1 more source

Adjuvant Chemotherapy Guided by a 21‐Gene Expression Assay in Breast Cancer

New England Journal of Medicine, 2018
BACKGROUND The recurrence score based on the 21‐gene breast cancer assay predicts chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it is low; however, there is uncertainty about the benefit of chemotherapy
J. Sparano, R. Gray, D. Makower, K. Pritchard, K. Albain, D. Hayes, C. Geyer, E. Dees, M. Goetz, J. Olson, T. Lively, S. Badve, T. Saphner, L. Wagner, T. Whelan, M. Ellis, S. Paik, W. Wood, P. Ravdin, M. Keane, H. G. Gomez Moreno, P. Reddy, T. Goggins, I. Mayer, A. Brufsky, D. Toppmeyer, V. Kaklamani, J. Berenberg, J. Abrams, G. Sledge   +29 more
semanticscholar   +1 more source

Antimicrobial resistance of nosocomial Pseudomonas aeruginosa isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 743 isolates of P.
Edelstein M.V., Sukhorukova M.V., Skleenova E.Yu., Ivanchik N.V., Mikotina A.V., Shek E.A., Dekhnich A.V., Azyzov I.S., Kozlov R.S., «MARATHON» Study Group   +9 more
doaj  

Impact of chemotherapy-induced nausea and vomiting on quality of life in indonesian patients with gynecologic cancer. [PDF]

, 2011
Patients reported a negative impact on the QoL of delayed emesis after chemotherapy. Poor prophylaxis of patients' nausea and vomiting after chemotherapy interferes with patients' QoL.
Atthobari, Jarir, Dwiprahasto, Iwan, Gelderblom, Hans, Guchelaar, Henk-Jan, Hakimi, Mohammad, Kaptein, Ad A, Mustofa, Mustofa, Nortier, Johan W R, Perwitasari, Dyah Aryani, Putter, Hein   +9 more
core   +1 more source

Antimicrobal resistance of nosocomial carbapenemase-producing Enterobacterales in Russia: results of surveillance, 2014-2016 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To assess the prevalence and antimicrobial susceptibility of carbapenemase-producing Enterobacterales (CPE). Materials and Methods. A total of 5539 Enterobacterales isolates recovered from hospitalized patients in 52 medical institutions ...
Shajdullina E.R., Edelstein M.V., Skleenova E.Yu., Sukhorukova M.V., Kozlov R.S.   +4 more
doaj   +1 more source