Results 91 to 100 of about 9,484 (238)

Essential oil composition from twelve varieties of basil (Ocimum spp) grown in Colombia

Journal of the Brazilian Chemical Society, 2003
Essential oil compositions of aerial parts from twelve basil cultivars (Ocimum spp) were analysed by gas chromatography-mass spectrometry (GC-MS). Ten of them were characterized by the presence of a high percentage of methyl cinnamate (35-80%), which ...
Viña Amparo, Murillo Elizabeth
doaj  

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

British Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck, Mario van der Stelt   +1 more
wiley   +1 more source

Chemotypic Diversity, Antimicrobial Activities, and Molecular Docking Analysis of Essential Oils from Four Elsholtzia Species in Northern Vietnam

Crops
An ethnobotanical survey in the northern mountainous region of Vietnam identified four Elsholtzia species, E. blanda, E. ciliata, E. communis, and E. penduliflora, growing naturally above 1500 m and traditionally used by local ethnic communities to treat
Nguyen Quynh Chi, Nguyen Thanh Tung, Do Thi Bich Diep, Do Thi Mai Dung, Nguyen Khac Tiep, Do Hong Quang, Hoang Quynh Hoa, Oleh Koshovyi, Hanh Dufat, Ain Raal, Do Quyen   +10 more
doaj   +1 more source

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

The FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam, Michelle Khai Khun Yap, Rafael Giacomazzi, Sérgio F. Sousa, Hock Siew Tan   +4 more
wiley   +1 more source

Bioactive Compound Profile and Nutrition Values of Kava (Piper methysticum) Cultivated in Fiji

Horticulturae
Piper methysticum G. Forst. (kava) is an important horticultural shrub of the Pacific, used as an ingredient of the intoxicating kava beverage, dietary supplement, and medicine around the globe.
Tibor Pasinszki, Deepti Darshani Devi, Melinda Krebsz   +2 more
doaj   +1 more source

Divergent roles of ent‐kaurene oxidase paralogs in rice momilactone biosynthesis

Journal of Integrative Plant Biology, EarlyView.
Rice contains a five‐gene tandem array of genes encoding members of the ent‐kaurene oxidase (KO) family, with OsKOL4 and OsKOL5 playing divergent roles in momilactone metabolism, but both acting in the production of antifungal and antibacterial phytoalexins, which are important for disease resistance.
Zhibiao Wang, Yiling Feng, Leiming You, Meimei Xu, Kristin Helwig, Riqing Li, Si Nian Char, Bing Yang, Reuben J. Peters   +8 more
wiley   +1 more source

Response of Melissa officinalis subsp. officinalis seedlings to Fe3O4‐NPs under in vitro conditions: physiological, biochemical and molecular analyses

Plant Biology, EarlyView.
Iron oxide nanoparticles influence the growth, antioxidant capacity, and gene activity of Melissa officinalis subsp. officinalis plants in vitro, revealing their potential as modulators of secondary metabolism. Abstract Application of iron oxide nanoparticles (NP) (Fe3O4‐NPs) in plant biotechnology presents new opportunities for enhancing metabolic ...
E. Bektaş, H. Şahin, H. İ. Güler, K. İ. Bektaş, K. Kaltalioğlu, N. E. Uzun   +5 more
wiley   +1 more source

Comparative analysis of essential oil composition and phenolic content in five Artemisia species

Notulae Scientia Biologicae
The genus Artemisia exhibits remarkable phytochemical diversity, largely associated with variations in essential oil composition and phenolic constituents. This study comparatively evaluated the essential oil profiles and total phenolic contents of five
Hacer DAĞAŞAN, Mehtap ÖZTEKİN, Ahmet YILMAZ, Mukaddes KOCAOĞLU KAVAS, Ayşe YILDIZ   +4 more
doaj   +1 more source

Genotype‐Dependent Chemical Diversity and Bioactivity in Purple Elephant Grass: A Metabolomics‐Guided Evaluation for Animal Nutrition

Natural Sciences, Volume 6, Issue 4, October 2026.
ABSTRACT Purple elephant grass (Cenchrus purpureus (Schumach.) Morrone) is a valuable forage crop with potential bioactive properties that influence animal health. This study presents a comprehensive metabolomic characterization of two purple elephant grass genotypes (T441 and T515) using high‐resolution mass spectrometry (HRMS), molecular networking ...
Salva Asghar, Erica A. Batista, Eric de Souza Gil, Gracimerio José Guarneire, Ana Mara F. Nunes, Sandra B. R. de Castro, Alessandra P. Carli, Caio César S. Alves, Juarez C. Machado, Abeer M. Alawi Al‐Sakkaf, Teresinha J. A. S. Andrade, Danielle F. Dias, Marisi G. Soares, Nerilson M. Lima   +13 more
wiley   +1 more source