Results 91 to 100 of about 14,379 (215)

Endophytic fungi from two isolated Bethencourtia palmensis populations: metabolomic and bioactivity fingerprinting

open access: yesPest Management Science, EarlyView.
We compared two island populations of Bethencourtia palmensis and their culturable endophytic fungi, revealing distinct plant chemistries and a higher biopesticidal potential in the endophytic fungi from La Palma population along with high potential for the discovery of novel compounds.
Jorge Rojas López‐Menchero   +4 more
wiley   +1 more source

Intraspecific stability of the thujone-rich chemotype of Thuja occidentalis L. in Estonia indicates persistent toxic potential [PDF]

open access: yesProceedings of the Estonian Academy of Sciences
The essential oil (EO) yield and chemical composition of Thuja occidentalis L. (Cupressaceae) growing in Estonia were investigated to assess intraspecific variability, chemotypic stability, and the consistency of toxic potential associated with thujone ...
Ain Raal, Oleh Koshovyi
doaj   +1 more source

Table_2_Genotypic and Environmental Effects on the Volatile Chemotype of Valeriana jatamansi Jones.xls

open access: yes, 2018
Valeriana jatamansi Jones is an aromatic medicinal herb and important alternative to V. officinalis, which is utilized for medicinal purposes in China and India and also as spices in India. Bioactive ingredients of V. jatamansi vary in different regions.
Zhonglin Sun (5494964)   +8 more
core   +1 more source

In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action

open access: yesPest Management Science, EarlyView.
In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier   +15 more
wiley   +1 more source

NIR-hyperspectral imaging and machine learning for non-invasive chemotype classification in Cannabis sativa L

open access: yes
The current public acceptance rate towards medical cannabis feasibility has led to a worldwide increase in this plant species production. Nevertheless, the currently transforming legal framework does not prevent the originally unlawful knowledge around ...
Amigo Rubio, José Manuel   +6 more
core   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff   +8 more
wiley   +1 more source

Chytrid and Planktothrix chemotype concentrations amplified from sediment of Kolbotnvannet, a lake in Southern Norway.

open access: yes, 2015
DNA concentrations, based on organic matter (OM) content and square root corrected, for amplicons of Planktothrix and chytrids recovered from each centimeter of a sediment core from Kolbotnvannet dating from 1980 to 2013 for A) Chemotype 1 and Chemotype ...
Thomas Rohrlack (319199)   +3 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

The geographic distribution and complex evolutionary history of the NX-2 trichothecene chemotype from Fusarium graminearum [PDF]

open access: yes, 2016
Fusarium graminearum and 21 related species comprising the F. sambucinum species complex lineage 1 (FSAMSC-1) are the most important Fusarium Head Blight pathogens of cereal crops world-wide.
Chulze, Sofia Noemi   +22 more
core   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck   +1 more
wiley   +1 more source

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