Results 91 to 100 of about 12,690 (274)
ToxinsFusarium graminearum (Fg) is the primary causal agent of Fusarium head blight (FHB) in wheat, barley, and other small grains in North America and worldwide.
Nicholas A. Rhoades +3 more
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Unusual backfolded binding poses of BAZ2A bromodomain binders
Acta Crystallographica Section D, EarlyView.We identified BAZ2A‐binding compounds assuming a peculiar, almost enclosed, conformation. These molecules pose a basis for the development of potent BAZ2A macrocyclic inhibitors, as performed for other bromodomains.BAZ2A is a large multidomain protein overexpressed in aggressive prostate cancer, where it potentiates migration and invasion of other ...
Andrea Dalle Vedove +5 more
wiley +1 more source
Pharmacognosy and Chemotypes of Passionflower (Passiflora incarnata L.)
Biological and Pharmaceutical Bulletin, 2010 Passionflower (Passiflora incarnata L.) is used in phytotherapy as a mild sedative and anxiolytic agent. In the literature it is clear this plant shows considerable qualitative and quantitative variability with respect to its content of C-glycosyl flavones, some of which are used as marker compounds for extracts.
Wohlmuth, Hans +3 more
openaire +5 more sources
World Journal of Traditional Chinese MedicineObjective: The study aimed to explore novel artemisinin plant sources as an alternative to Artemisia annua, to study the effect of habitat height on artemisinin concentration, and to find out the existence of chemotypes in Artemisia species.
Abdul Mannan +4 more
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Agricultural and Forest Entomology, EarlyView.Optimal growing temperatures varied with mountain pine beetle‐associated fungal species. There was only a marginal impact of temperature on the response of fungi to defensive monoterpenes of novel host pine. Interspecific facilitation occurred for Leptiographuim longiclavatum when grown in Ophiostoma montium‐induced treatments at optimal temperatures ...
Adrienne C. Bailey +4 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
, 2018 Valeriana jatamansi Jones is an aromatic medicinal herb and important alternative to V. officinalis, which is utilized for medicinal purposes in China and India and also as spices in India. Bioactive ingredients of V. jatamansi vary in different regions.
Zhonglin Sun (5494964) +8 more
core +1 more source
The geographic distribution and complex evolutionary history of the NX-2 trichothecene chemotype from Fusarium graminearum [PDF]
, 2016 Fusarium graminearum and 21 related species comprising the F. sambucinum species complex lineage 1 (FSAMSC-1) are the most important Fusarium Head Blight pathogens of cereal crops world-wide.
Chulze, Sofia Noemi +22 more
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Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways
British Journal of Pharmacology, EarlyView.Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck +1 more
wiley +1 more source
Essential oils from Leptospermums of the Sunshine Coast and Northern Rivers Regions
Chemistry Central Journal, 2012 Background Around the turn of this century, the oil yield and chemical composition of Australian Leptospermum species was analysed. Since that time, research has been focused on their use as phytomedicines. The oil yield and composition of essential oils
Windsor Sarah Alison, Brooks Peter
doaj +1 more source