Results 101 to 110 of about 14,379 (215)
The FEBS Journal, EarlyView.DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam +4 more
wiley +1 more source
Genotype to Chemotype Analysis in Sage (Salvia officinalis L., Lamiaceae)
, 2015 Chemotypes (or chemovars) are chemically distinct entities within a plant species based on genetic variation. Their occurrence is in mono- and sesquiterpenes (principal constituents of essential oils) exceptionally frequent.
MAGGI, Filippo
core +1 more source
Oral Ulcerations and Phytotherapy: Potential Role of Helichrysum Essential Oil—A Literature Review
Oral Diseases, EarlyView.ABSTRACT Background Recurrent aphthous stomatitis (RAS) is a common yet therapeutically challenging chronic inflammatory disease of the oral mucosa, characterized by recurrent, painful ulcerations that substantially affect patients' quality of life. Objective This review summarizes current evidence on phytotherapy in RAS, with particular focus on the ...
Ruzica Ivkovic +4 more
wiley +1 more source
Plant Biology, EarlyView.Iron oxide nanoparticles influence the growth, antioxidant capacity, and gene activity of Melissa officinalis subsp. officinalis plants in vitro, revealing their potential as modulators of secondary metabolism. Abstract Application of iron oxide nanoparticles (NP) (Fe3O4‐NPs) in plant biotechnology presents new opportunities for enhancing metabolic ...
E. Bektaş +5 more
wiley +1 more source
Drug Development Research, Volume 87, Issue 7, November 2026.ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disease, and cholinergic dysfunction is considered one of the fundamental pathological factors of this disease. Guided by the clinically used acetylcholinesterase (AChE) inhibitor donepezil, we explored trimetazidine dihydrochloride as an accessible starting scaffold to generate ...
Muhammed Oğuzhan Doğan +6 more
wiley +1 more source
Essential oil composition from twelve varieties of basil (Ocimum spp) grown in Colombia
Journal of the Brazilian Chemical Society, 2003 Essential oil compositions of aerial parts from twelve basil cultivars (Ocimum spp) were analysed by gas chromatography-mass spectrometry (GC-MS). Ten of them were characterized by the presence of a high percentage of methyl cinnamate (35-80%), which ...
Viña Amparo, Murillo Elizabeth
doaj
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Bioactive Compound Profile and Nutrition Values of Kava (Piper methysticum) Cultivated in Fiji
HorticulturaePiper methysticum G. Forst. (kava) is an important horticultural shrub of the Pacific, used as an ingredient of the intoxicating kava beverage, dietary supplement, and medicine around the globe.
Tibor Pasinszki +2 more
doaj +1 more source
Comparing genotype and chemotype of Fusarium graminearum from cereals in Ontario, Canada
, 2019 Fusarium graminearum is responsible for production of the mycotoxin deoxynivalenol (DON) on maize and wheat in Ontario, Canada. It has been understood since the early 1980s that in most parts of Canada, the predominant chemotype of F.
Justin B. Renaud (1422631) +7 more
core +1 more source