Results 121 to 130 of about 12,690 (274)

Metabolic Plasticity and Terpenoid Modulation in Zanthoxylum armatum Callus Cultures: Chemical Composition and Biotechnological Perspectives

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 884-899, July 2026.
Graphical abstract illustrating the metabolic dynamics and regulation of terpenoid production in Zanthoxylum armatum callus cultures. On the left, callus initiation and growth from explants are shown, followed by the establishment of suspension cultures.
Sumit Purohit, Balwant Rawat, Ravendra Kumar, Mrinalini Agarwal, Somya Sinha, Shivani Negi, Namini Joshi, Akshita Raj, Prabhakar Semwal, A. Dheerani, Janhvi Mishra Rawat, Mozaniel Santana de Oliveira   +11 more
wiley   +1 more source

Bioactive Compound Profile and Nutrition Values of Kava (Piper methysticum) Cultivated in Fiji

Horticulturae
Piper methysticum G. Forst. (kava) is an important horticultural shrub of the Pacific, used as an ingredient of the intoxicating kava beverage, dietary supplement, and medicine around the globe.
Tibor Pasinszki, Deepti Darshani Devi, Melinda Krebsz   +2 more
doaj   +1 more source

Phytochemical Composition and Potential Bioactivity With ADMET Analysis of Selected Species From Myrtaceae Family

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 1002-1029, July 2026.
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi, Vaishnavi Rawat, Ravendra Kumar, Stefania Garzoli, Anil Kumar Pant, Marcin Stocki, Valery A. Isidorov, Om Prakash, Dharmendra Singh Rawat   +8 more
wiley   +1 more source

In vitro characterization, structural optimization and in silico pharmacophore modeling of a new antiplasmodial chemotype

, 2019
Malaria is the most common parasitic disease worldwide, and the third deadliest infection after HIV and tuberculosis. Due to the risk of diffusion of artemisinin resistance in Africa, new drugs for ensuring efficacious antimalarial treatment are urgently
Ivan Bassanini, Donatella Taramelli, Sergio Romeo, Silvia Parapini, Nicoletta Basilico   +4 more
core  

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Chemotypic Diversity, Antimicrobial Activities, and Molecular Docking Analysis of Essential Oils from Four Elsholtzia Species in Northern Vietnam

Crops
An ethnobotanical survey in the northern mountainous region of Vietnam identified four Elsholtzia species, E. blanda, E. ciliata, E. communis, and E. penduliflora, growing naturally above 1500 m and traditionally used by local ethnic communities to treat
Nguyen Quynh Chi, Nguyen Thanh Tung, Do Thi Bich Diep, Do Thi Mai Dung, Nguyen Khac Tiep, Do Hong Quang, Hoang Quynh Hoa, Oleh Koshovyi, Hanh Dufat, Ain Raal, Do Quyen   +10 more
doaj   +1 more source

Evaluation of Enzyme Inhibition and Kinetic Profiles of Origanum Essential Oils on Metabolic and Central Nervous System Targets

Natural Sciences, Volume 6, Issue 3, July 2026.
The essential oils of three Origanum species were chemically characterized and evaluated for their antioxidant and enzyme inhibitory activities. The different compositions confer selective bioactivities: O. vulgare exhibits good antioxidant and α‐glucosidase inhibitory activity, O. majorana shows promising tyrosinase inhibition, and O.
Giuseppe Amato, Lucia Caputo, Laura De Martino, Daniela Grulova, Barbara Borczak, Joanna Kapusta‐Duch, Vincenzo De Feo   +6 more
wiley   +1 more source

Comparative analysis of essential oil composition and phenolic content in five Artemisia species

Notulae Scientia Biologicae
The genus Artemisia exhibits remarkable phytochemical diversity, largely associated with variations in essential oil composition and phenolic constituents. This study comparatively evaluated the essential oil profiles and total phenolic contents of five
Hacer DAĞAŞAN, Mehtap ÖZTEKİN, Ahmet YILMAZ, Mukaddes KOCAOĞLU KAVAS, Ayşe YILDIZ   +4 more
doaj   +1 more source

Effects of pre-incubation time on falcipain-3 IC₅₀ values for inhibitors of different chemotype.

, 2013
Effects of pre-incubation time on falcipain-3 IC50 values for inhibitors of different chemotype.
Jiri Gut (145726), Adam R. Renslo (114387), Michelle R. Arkin (114394), Anjan Debnath (352163), Zachary B. Mackey (138942), Jennifer Legac (265204), Philip J. Rosenthal (47478), James H. McKerrow (113918), Kenny K. H. Ang (145735), Joseline Ratnam (352161), Katarzyna M. Skrzypczynska (352162), Juan C. Engel (145730), Elizabeth Hansell (203763)   +12 more
core   +1 more source

Reframing Wnt/β‐Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley   +1 more source