Description and Significance of Plant Chemotypes*
openaire +1 more source
Artemisinin-Related Therapeutic Strategies for Autoimmune Thyroiditis: Chemokine-Receptor Networks, Spatial Thyroid Biology, and Molecular Mechanisms. [PDF]
Sun Y, Yang X, Zhu Q, Yang R.
europepmc +1 more source
Leaf age influences metabolomic profiling but not bioactivity of Eucalyptus globulus essential oils. Leaf age affects volatile levels of young and adult E. globulus oils, but not their bioactivity. Young leaf essential oil had higher contents of α‐ and β‐pinene. AEEO had higher levels of 1,8‐cineole and trans‐pinocarveol.
Mafalda Pinto +11 more
wiley +1 more source
Thymol Chemotype Thymus vulgaris L. Hydrolate: Volatile Chemical Fraction Composition and Antimicrobial Activity Against Bacterial and Fungal Pathogens. [PDF]
Garzoli S +4 more
europepmc +1 more source
Chemical Profile and Antibacterial Activity of Cymbopogon Citratus Leaf Essential Oil
The essential oil of Cymbopogon citratus was chemically characterized by GC–MS and evaluated for antibacterial activity against clinically relevant Gram‐positive and Gram‐negative bacteria. Citral isomers (geranial and neral) were identified as the major constituents, and the oil exhibited selective bactericidal and bacteriostatic effects, supporting ...
Francarlos Guimarães Rodrigues +7 more
wiley +1 more source
Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context. [PDF]
Banjanac T +15 more
europepmc +1 more source
The 2‐aminopyridine moiety of KPT‐7523 binds p21‐activated kinase 4 and nicotinamide phosphoribosyltransferase, enabling a versatile design for multi‐target cancer therapy.Simultaneous inhibition of oncogenic signaling and metabolic pathways represents a promising approach for cancer therapy.
Jaehui Park +13 more
wiley +1 more source
Mapping the inhibition landscape of P-glycoprotein via conformational ensemble docking. [PDF]
Elbahnsi A +7 more
europepmc +1 more source
Multi‐omics (proteomics, metabolomics, and single‐cell/spatial transcriptomics) provides a systems framework to distinguish on‐target efficacy from off‐target and toxicity signatures of chemically modified nucleic acid therapeutics, enabling omics‐guided structure–activity and safety optimisation from discovery to clinical translation. ABSTRACT Nucleic
Gurjit Kaur Bhatti +6 more
wiley +1 more source
Long-term neighbor identity influences effectiveness of sagebrush responses to damage-induced volatiles of those neighbors. [PDF]
Shiojiri K +3 more
europepmc +1 more source

