Results 151 to 160 of about 14,379 (215)

Seasonal Effect on the Chemical Composition of Lippia alba Volatile Chemotypes. [PDF]

open access: yesChem Biodivers
Barroso Neto MS   +5 more
europepmc   +1 more source

Sodium Channel Blockers Demonstrate Binding Affinity for the Tandem Tudor Domain of the Epigenetic Hub UHRF1

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
An investigation of the tandem Tudor domain (TTD) domain of UHRF1 identified and extensively characterized the local anesthetic hydroxyprocaine as a strong ligand capable of activating related genes such as p53 and also highlighted a new, potentially druggable intramolecular interaction between TTD and UBL.
Efstratios Tsakalidis   +16 more
wiley   +1 more source

Organ-specific terpenoid responses in Tanacetum vulgare are chemotype-dependent. [PDF]

open access: yesPlant Biol (Stuttg)
Newrzella H   +12 more
europepmc   +1 more source

Precision Chemistry for Protein Lysine Modification

open access: yesChemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

Molecular LEGION: incalculably large coverage of chemical space around the NLRP3 target. [PDF]

open access: yesSci Data
Zagribelnyy B   +11 more
europepmc   +1 more source

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