Results 151 to 160 of about 15,517 (273)

Nutritional Composition, Therapeutic Benefits, and Functional Food Potential of Coleus amboinicus: A Comprehensive Review

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Coleus amboinicus is a nutrient‐rich herb containing vitamins (A‐, C‐, B‐complex), minerals (Ca, Mg, Fe, K), dietary fiber, and potent bioactives such as rosmarinic acid, quercetin, thymol, and carvacrol. These compounds contribute to antioxidant, anti‐inflammatory, antimicrobial, prebiotic, and cardioprotective benefits.
Shani Upadhyay   +2 more
wiley   +1 more source

The Chemical Structures, Neuroprotective Effects, Structure–Activity Relationships, and Applications of Flavonoids, Phenolic Acids, Terpenoids, and Sterols in Dandelion: A Review

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
This review systematically summarizes the chemical structures and structure–activity relationships of key bioactive compounds in dandelion, including flavonoids, phenolic acids, terpenoids, and sterols. It highlights their neuroprotective mechanisms against neuroinflammation and oxidative stress, while outlining their promising dual applications in the
Hongye Li   +9 more
wiley   +1 more source

Exploring the Nutraceutical Potential of Achillea millefolium L.: Phytochemical Composition, Biological Activities, and Industrial Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed   +14 more
wiley   +1 more source

Disinfecting capacity of essential oil of Thymus pulegioides L. (lamiaceae) chemotypes against phytopathogenic Pseudomonas species

open access: yes
The antibacterial activity of essential oils of T. pulegioides chemotypes — geraniol/geranial/neral (G/G/N), thymol (T) and linalool (L) — was studied against the seven phytopathogenic Pseudomonas species isolated from vegetables.
Tekorienė, R., Ložienė, K.
core   +1 more source

Essential Oil Formulations From Salvia officinalis, Ormenis africana, and Mentha pulegium: Chemical Profiles and Insecticidal Activity Against Myzus persicae

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
The insecticidal potential of formulations based on Salvia officinalis, Ormenis africana, and Mentha pulegium essential oils was investigated against Myzus persicae. The combination of the three oils provided the most effective control, showing strong activity in laboratory assays and greenhouse trials.
Asma El Ayeb‐Zakhama   +9 more
wiley   +1 more source

Single‐Sequence Deep Learning Delivers Crystal‐Quality Models of Covalent K‐Ras G12 Hotspot Complexes

open access: yesIUBMB Life, Volume 78, Issue 6, June 2026.
ABSTRACT Structure‐based design of covalent drugs has achieved tremendous success by understanding and leveraging the three‐dimensional interactions between small‐molecule drug candidates and their protein targets. However, this approach traditionally relies on high‐resolution co‐complex structures obtained by X‐ray crystallography, NMR, or cryo‐EM ...
Sungwon Jung   +2 more
wiley   +1 more source

G Protein‐Coupled Receptor 17 (Gpr17) Enhances Leptin and Insulin Sensitivity in Lean and Obese Mouse Models

open access: yesObesity, Volume 34, Issue S1, Page 77-87, June 2026.
This study identifies G protein‐coupled receptor 17 (Gpr17) as a novel regulator of leptin and insulin sensitivity. Using complementary knockout models, we demonstrate that Gpr17 deletion enhances energy expenditure, restores leptin responsiveness, and improves insulin sensitivity, revealing Gpr17 as a potential therapeutic GPCR target for obesity and ...
Xun Sun   +8 more
wiley   +1 more source

Evolution of Thiosemicarbazones: From First‐ to Second‐Generation Metal Chelators and Their Reactive Oxygen Species‐Mediated Effects in Melanoma

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Thiosemicarbazones (TSC) have demonstrated promise as new chemotherapeutic agents against melanoma in both in vitro and In vivo studies. TSC are powerful metal coordinating agents, coordinating transition metal ions such as zinc, copper and iron in multiple oxidation states. It is this metal coordination that imparts the anticancer activity.
Rohina Alim   +2 more
wiley   +1 more source

Liquid Chromatography‐Electrospray Ionization‐Tandem Mass Spectrometry Profiling, Antioxidant, Antibacterial, and Antidiabetic Properties of Fagonia cretica L.: Insights From In Vitro and In Silico Approaches

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Fagonia cretica L.: Phytochemical investigation and exploration of bioactivity through in vitro and in silico approaches. This study provides an integrative evaluation of the aqueous extract of Fagonia cretica L., a species long employed in traditional medicine but insufficiently characterized through systematic experimental and computational ...
Neghmouche Nacer Salah   +8 more
wiley   +1 more source

Evaluation of the Phytochemical Composition, Antioxidant Activity, and Enzyme Inhibitory Potential of Salvia heldreichiana Within the Framework of Molecular Docking and CAVER Tunnel Analysis

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Methanolic extract of Salvia heldreichiana is characterized by HPLC and GC–MS analyses and evaluated for antioxidant and anti‐Alzheimer activities. Major phenolic compounds are identified, while molecular docking analysis supports the interaction of bioactive constituents with target enzymes, highlighting the therapeutic potential of S.
Erdi Can Aytar   +5 more
wiley   +1 more source

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