Results 41 to 50 of about 17,521 (222)

Naturally Occurring Fusarium Species and Mycotoxins in Oat Grains from Manitoba, Canada

open access: yesToxins, 2021
Fusarium head blight (FHB) can lead to dramatic yield losses and mycotoxin contamination in small grain cereals in Canada. To assess the extent and severity of FHB in oat, samples collected from 168 commercial oat fields in the province of Manitoba ...
M. Nazrul Islam   +7 more
doaj   +1 more source

HTS-Driven Discovery of New Chemotypes with West Nile Virus Inhibitory Activity

open access: yesMolecules, 2010
West Nile virus (WNV) is a positive sense, single-stranded RNA virus that can cause illness in humans when transmitted via mosquito vectors. Unfortunately, no antivirals or vaccines are currently available, and therefore efficient and safe antivirals are
Qianjun Li   +10 more
doaj   +1 more source

Chemical Variation and Environmental Influence on Essential Oil of Cinnamomum camphora

open access: yesMolecules, 2023
Cinnamomum camphora is a traditional aromatic plant used to produce linalool and borneol flavors in southern China; however, its leaves also contain many other unutilized essential oils.
Ting Zhang   +7 more
doaj   +1 more source

Crop Yield and Essential Oil Composition of Two Thymus vulgaris Chemotypes along Three Years of Organic Cultivation in a Hilly Area of Central Italy

open access: yesMolecules, 2021
Thymus vulgaris L. is one of the most commonly used medicinal and aromatic plants (MAPs), owing to a range of therapeutic properties of its essential oil.
Basma Najar   +4 more
doaj   +1 more source

Diversity of Peptides Produced by Nodularia spumigena from Various Geographical Regions

open access: yesMarine Drugs, 2012
Cyanobacteria produce a great variety of non-ribosomal peptides. Among these compounds, both acute toxins and potential drug candidates have been reported. The profile of the peptides, as a stable and specific feature of an individual strain, can be used
Lisa Spoof   +5 more
doaj   +1 more source

Development of a generic PCR detection of deoxynivalenol- and nivalenol-chemotypes of Fusarium graminearum

open access: yes, 2005
Based on the intergenic sequences of Tri5¿Tri6 genes involved in the mycotoxin pathways of Fusarium species, a generic PCR assay was developed to detect a 300 bp fragment of deoxynivalenol (DON)-chemotypes and a 360 bp sequence of nivalenol (NIV ...
Scholten, O.E.   +5 more
core   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

Variations in the Chemical Composition of Essential Oils in Native Populations of Korean Thyme, Thymus quinquecostatus Celak.

open access: yesMolecules, 2022
The genus Thymus (Lamiaceae) contains numerous medicinally important species. Among them, Thymus quinquecostatus Celak. has been extensively utilized as a traditional medicine and a food flavoring agent in the Korean peninsula, owing to its unique aroma.
Minju Kim   +3 more
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America

open access: yesMolecules, 2018
The Verbenaceae family includes 2600 species grouped into 100 genera with a pantropical distribution. Many of them are important elements of the floras of warm-temperature and tropical regions of America.
Cristina M. Pérez Zamora   +2 more
doaj   +1 more source

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