Results 51 to 60 of about 17,521 (222)

Influence of Abiotic Factors on the Phytochemical Profile of Two Species of Artemisia: A. herba alba Asso and A. mesatlantica Maire

International Journal of Plant Biology, 2022
The species of Artemisia are well known in the Mediterranean region, especially in Morocco, for their traditional uses and health benefit. In this study, we were interested in two species of Artemisia, namely A. herba alba Asso and A. mesatlantica Maire.
Sanae Amine, Mohamed Bouhrim, Hamza Mechchate, Atika Ailli, Mohamed Radi, Sevser Sahpaz, Smail Amalich, Malika Mahjoubi, Touriya Zair   +8 more
doaj   +1 more source

Clinically used antimalarial chemotypes and their corresponding MoA.

, 2013
Clinically used antimalarial chemotypes and their corresponding MoA.
Andreas Spitzmüller (473662), Jordi Mestres (168498)   +1 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Chemical constituents of sea buckthorn (Hippophae rhamnoides L.) fruit in populations of central Alborz Mountains in Iran [PDF]

Research Journal of Pharmacognosy, 2017
Background and objectives: Hippophae rhamnoides L. known as sea buckthorn is a deciduous medicinal shrub belonging to Elaeagnaceae family. In this study, the most important chemical constituents of sea buckthornwere evaluated in wild populations of ...
A. Kuhkheil, H. Naghdi Badi, A. Mehrafarin, V. Abdossi   +3 more
doaj  

Chemical Composition, Antimicrobial and Antioxidant Activities of Essential Oils from Two Avicennia schaueriana Stapf & Leechm. Ex Moldenke (Acanthaceae) Populations

Medicines, 2017
Background: Avicennia schaueriana Stapf & Leechm. ex Moldenke (Acanthaceae) is a native species from the Brazilian mangroves presenting ecological and economic significance.
Kamilla N. Machado, Telma M. Kaneko, Maria Cláudia M. Young, Cynthia Murakami, Inês Cordeiro, Paulo Roberto H. Moreno   +5 more
doaj   +1 more source

Studies on Chemotypes of Cinnamomum Camphora

, 2011
Gas chromatography coupled with mass spectrometry (GC-MS) was applied to analyze the essential oil extracted from the leaves of 50 individual plants of Cinnamomum camphora, which were collected from the same mountain in Jiangxi province of China.
Yong Ming Luo, Shi Rong Li, Xiao Yin Yin
core   +1 more source

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

Bio-Herbicidal Potential of the Essential Oils from Different Rosmarinus officinalis L. Chemotypes in Laboratory Assays

Agronomy, 2020
The current study aimed to assess the allelopathic effect of Rosmarinus officinalis L. essential oils (EOs) to define the potent effect against weed species, by exploring distinct chemotypes and their main compounds.
Jihane El Mahdi, Waed Tarraf, Claudia Ruta, Lea Piscitelli, Adel Aly, Giuseppe De Mastro   +5 more
doaj   +1 more source

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

Advanced Science, EarlyView.
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong, Sunny A. Tang, Yifan Deng, Zhihan Nan, Alison X. Gao, Gregory A. Michaud, Simone Bonazzi, Frédéric Berst, Frédéric J. Zécri, Shuang Liu, William J. Gibson, Stuart L. Schreiber   +11 more
wiley   +1 more source

Seasonal Variation of Essential Oils Composition in a Genetically Diverse Population of Lippia alba and Its Influence on Antibacterial Activity [PDF]

Chem Biodivers
The essential oils profile, antibacterial activity and leaf nutrients contents of a Lippia alba genetically diverse population are examined regarding seasonal harvesting. ABSTRACT Lippia alba is an aromatic plant whose essential oils (EOs) have been characterized as promising antimicrobial agents. It has been established that L.
Santos M, Botelho T, Delarmelina C, Siqueira W, Duarte M, Marques M, Mondego J.   +6 more
europepmc   +2 more sources