Results 61 to 70 of about 15,517 (273)

Clinically used antimalarial chemotypes and their corresponding MoA.

, 2013
Clinically used antimalarial chemotypes and their corresponding MoA.
Andreas Spitzmüller (473662), Jordi Mestres (168498)   +1 more
core   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

Chemical constituents of sea buckthorn (Hippophae rhamnoides L.) fruit in populations of central Alborz Mountains in Iran [PDF]

Research Journal of Pharmacognosy, 2017
Background and objectives: Hippophae rhamnoides L. known as sea buckthorn is a deciduous medicinal shrub belonging to Elaeagnaceae family. In this study, the most important chemical constituents of sea buckthornwere evaluated in wild populations of ...
A. Kuhkheil, H. Naghdi Badi, A. Mehrafarin, V. Abdossi   +3 more
doaj  

Morphological and chemical variability of common oregano (Origanum vulgare L. subsp. vulgare) occurring in eastern Poland

Herba Polonica, 2018
Introduction: Common oregano is an important medicinal and aromatic plant, characterized by a high morphological and chemical variability.
Kosakowska Olga, Czupa Weronika
doaj   +1 more source

Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America

Molecules, 2018
The Verbenaceae family includes 2600 species grouped into 100 genera with a pantropical distribution. Many of them are important elements of the floras of warm-temperature and tropical regions of America.
Cristina M. Pérez Zamora, Carola A. Torres, María B. Nuñez   +2 more
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Chemical Composition, Antimicrobial and Antioxidant Activities of Essential Oils from Two Avicennia schaueriana Stapf & Leechm. Ex Moldenke (Acanthaceae) Populations

Medicines, 2017
Background: Avicennia schaueriana Stapf & Leechm. ex Moldenke (Acanthaceae) is a native species from the Brazilian mangroves presenting ecological and economic significance.
Kamilla N. Machado, Telma M. Kaneko, Maria Cláudia M. Young, Cynthia Murakami, Inês Cordeiro, Paulo Roberto H. Moreno   +5 more
doaj   +1 more source

Ten differential phytohormone metabolites of two chemotypes of P. cablin.

, 2023
Ten differential phytohormone metabolites of two chemotypes of P. cablin.
Mengling He (9472802), Hanjing Yan (9472805), Wenyi Chen (1365132), Xiaohua Ou (8157216), Qing Zeng (494174), Yaling Yan (10522498), Hongyi Zhang (431841)   +6 more
core   +1 more source

Hydrothermal Humification of Biomass for Circular Carbon Management in Sustainable Agro‐Ecosystems

Advanced Science, EarlyView.
This article provides a comprehensive overview of biomass hydrothermal humification for building sustainable agro‐ecosystems. It examines the chemical transformation mechanisms and the functional benefits of the produced humic acids in soil remediation.
Ziyun Liu, Zonglu Yao, Yuanhui Zhang, Huiyan Zhang, Lixin Zhao   +4 more
wiley   +1 more source