Bile acid biosynthesis has been believed to be regulated by negative feedback control; however, recent experiments have cast considerable doubts on the concept. The aim of the study was to examine the consensus of the negative feedback regulation of bile
K Fukushima+6 more
doaj
Background Diabetic kidney disease (DKD) is the major complication of diabetes concomitant with gut dysbiosis and glycometabolic disorder, which are strongly associated with bile acid (BA) metabolism. Yet studies investigating the BA metabolism involving
Qing Zhang+6 more
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Chenodeoxycholic Acid Enhances the Effect of Sorafenib in Inhibiting HepG2 Cell Growth Through EGFR/Stat3 Pathway. [PDF]
Zhang Y+6 more
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Low-cholesterol diet in patients with gall stones taking chenodeoxycholic acid. [PDF]
J. McK. Watts, R.H.L. Down, M.J. Whiting
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27-Hydroxycholesterol: production rates in normal human subjects
We attempted to quantitate production of bile acid via the 27-hydroxylation pathway in six human subjects. After bolus intravenous injection of known amounts of [24-14C]cholic acid and [24-14C]chenodeoxycholic acid, each subject underwent a constant ...
William C. Duane, Norman B. Javitt
doaj
On the Turnover and Excretory Products of Cholic and Chenodeoxycholic Acid in Man
Henry Danielsson+4 more
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Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol.
Diosgenin and beta-sitosterol (1% in diet) were administered to CRJ:CD-1 male mice for 15 days, in order to examine the changes in bile acid metabolism.
K Uchida+5 more
doaj
Cerebrotendinous Xanthomatosis: diversity of presentation and refining treatment with chenodeoxycholic acid. [PDF]
Islam M, Hoggard N, Hadjivassiliou M.
europepmc +1 more source
Quantitative aspects of the interaction of bile acids with human serum albumin.
The interaction of human serum albumin with twelve bile acids (ba) has been studied by equilibrium dialysis technique using 3H- and 14C-labeled bile acids.
A Roda+4 more
doaj
Corrigendum to "Chenodeoxycholic acid suppresses AML progression through promoting lipid peroxidation via ROS/p38 MAPK/DGAT1 pathway and inhibiting M2 macrophage polarization" [Redox Biol. 56 (2022) 102452]. [PDF]
Liu J+9 more
europepmc +1 more source