Results 51 to 60 of about 236,944 (258)
Bendiocarbamate Toxicity in the Chick Embryo
Folia Biologica, 2009 Carbamate pesticides generally possess low toxicity for warm-blooded vertebrates, but developmental data are scarce. We have therefore evaluated embryotoxicity of choline esterase inhibitor bendiocarbamate in the chick embryo. The pesticide was dissolved in 5% acetone in distilled water and a volume of 200 μl was administered over ...
E, Peterovová +4 more
openaire +2 more sources
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
A detailed description of an economical setup for electroporation of chick embryos in ovo
Brazilian Journal of Medical and Biological Research, 2013 One of the challenges of the postgenomic era is characterizing the function and regulation of specific genes. For various reasons, the early chick embryo can easily be adopted as an in vivo assay of gene function and regulation.
R.M. Borges +8 more
doaj +1 more source
Advanced Science, EarlyView.In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang +18 more
wiley +1 more source
Results of hatching and rearing broiler chickens in different incubation systems
Poultry Science, 2021 Hatchery efficiency is based on hatchability and the number of salable chicks. The hatchery sector has been seeking new alternatives to optimize production rates, including the use of different systems (multistage [MS] or single-stage [SS] machines) to ...
Mariana A. Mesquita +8 more
doaj +1 more source
Lipid Metabolism in Chick Embryos
Poultry Science, 1981 Embryonic lipids exhibit a more saturated fatty acid composition than the yolk lipids from which the embryo develops. Neither selective embryonic uptake of saturated fatty acids from yolk nor selective embryonic oxidation of unsaturated fatty acids appears to be a valid explanation for this observation.
openaire +3 more sources
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
Activity of Melatonin Against Gastric Cancer Growth in a Chick Embryo Tumor Xenograft Model
Cancer Management and Research, 2021 Rixiong Wang,1,2 Hui Liu,3,4 Jun Song,3,4 Qing Wu1,2 1Department of Oncology, the First Affiliated Hospital of Fujian Medical University, Fuzhou City, People’s Republic of China; 2Fujian Key Laboratory of Precision Medicine for Cancer, the First ...
Wang R, Liu H, Song J, Wu Q
doaj
A new oxidative stress model, 2,2-azobis(2-amidinopropane) dihydrochloride induces cardiovascular damages in chicken embryo. [PDF]
PLoS ONE, 2013 It is now well established that the developing embryo is very sensitive to oxidative stress, which is a contributing factor to pregnancy-related disorders.
Rong-Rong He +9 more
doaj +1 more source
Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert +31 more
wiley +1 more source