Results 71 to 80 of about 38,045 (222)

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim, Cheoljin Park, Donghee Kim, Wonjun Jeong, Jinsoo Lee   +4 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

The European honey buzzard (Pernis apivorus) as an ally for the control of the invasive yellow‐legged hornet (Vespa velutina nigrithorax)

Pest Management Science, Volume 81, Issue 4, Page 2237-2247, April 2025.
The predatory effect of the honey‐buzzard affects the reproductive performance of Asian‐hornet colonies, decreasing the density of workers over distance and time. The foraging distances of the honey‐buzzard concentrates within the first 2000 m from nest, which supports the results observed.
Jorge Ángel Martín‐Ávila, Luisa María Díaz‐Aranda, José Manuel Fernández‐Pereira, Salvador Rebollo   +3 more
wiley   +1 more source

Endocrine cells in atresic chick embryo intestine: histochemical and immunohistochemical study

European Journal of Histochemistry, 2009
Intestinal motility disorders are an important problem in the postoperative management of patients with intestinal atresia. Intestinal motility could be initiated by luminal factors that activate intrinsic and extrinsic primary afferent nerves involved ...
T. Renda, S.M. Baglaj, I. D’Este, E. Parisi Salvi, I. Nofroni, R. Vaccaro   +5 more
doaj   +3 more sources

A new gestational diabetes mellitus model: hyperglycemia-induced eye malformation via inhibition of Pax6 in the chick embryo

Disease Models & Mechanisms, 2016
Gestational diabetes mellitus (GDM) is one of the leading causes of fetal malformations. However, few models have been developed to study the underlying mechanisms of GDM-induced fetal eye malformation. In this study, a high concentration of glucose (0.2 
Shi-Jie Zhang, Yi-Fang Li, Rui-Rong Tan, Bun Tsoi, Wen-Shan Huang, Yi-Hua Huang, Xiao-Long Tang, Dan Hu, Nan Yao, Xuesong Yang, Hiroshi Kurihara, Qi Wang, Rong-Rong He   +12 more
doaj   +1 more source

Experimental Evidence for Mobilization of Mercury From the Eggshell by the Developing Embryo in an Avian Model Organism

Environmental Toxicology, EarlyView.
ABSTRACT Of the many pollutants wildlife is exposed to, mercury ranks among the most toxic. In birds, mercury does not only accumulate within generations, but also is transferred across generations via maternal offloading in eggs, with higher mercury concentrations found in shells of unhatched eggs.
Matteo Beccardi, Justine Bertram, Sandra Bouwhuis, Pablo Salmón, Peter J. Schupp, Oscar Vedder   +5 more
wiley   +1 more source

Reinforcing the utility of chick embryo model to in vivo evaluate engraftment of human leukemic stem cells

Journal of the Egyptian National Cancer Institute, 2018
Background and Objective: Development of appropriate translational in vivo models is a prerequisite for personalized management of leukemic patients. Indeed, several immunodeficient mice models were developed for leukemias with main limitations due to ...
Arwa Farhat, Eiad Ali-Deeb, Amin Sulaiman, Majd Aljamali   +3 more
doaj   +1 more source

Snowmelt predicts earlier breeding across the latitudinal range of an Arctic nesting seabird, the Little Auk (Alle alle)

Journal of Animal Ecology, EarlyView.
Multi‐year monitoring of the crevice‐nesting High Arctic seabird, the Little Auk (Alle alle), across four colonies spanning distinct climatic regimes revealed that snowmelt timing is a key and consistent driver of breeding phenology. Earlier snowmelt advances access to nesting habitat, enabling birds to initiate reproduction sooner. These findings show
Martyna Syposz, Øystein Varpe, Sébastien Descamps, Jérôme Fort, David Grémillet, Ann Harding, Dariusz Jakubas, Dorota Kidawa, Nomikos Skyllas, Hallvard Strøm, Tom S. L. Versluijs, Katarzyna Wojczulanis‐Jakubas   +11 more
wiley   +1 more source

Flap Anatomies and Victorian Veils: Penetrating the Female Reproductive Interior

Gender &History, EarlyView.
ABSTRACT This article examines the reappearance in the early nineteenth century of anatomical flapbooks in the context of obstetrical education in Britain, America and France. It asks why liftable paper flaps were reintroduced at this time after their disappearance from medical atlases in the eighteenth century.
Margaret Carlyle, Marcia D. Nichols
wiley   +1 more source

The effect of different wavelengths of light during incubation on the development of rhythmic pineal melatonin biosynthesis in chick embryos

Animal, 2019
Rhythmic pineal melatonin biosynthesis develops in chick embryos incubated under a light (L)-dark (D) cycle of polychromatic white light. The spectral sensitivity of the embryonic pineal gland is not known and was investigated in this study.
A. Drozdova, M. Okuliarova, M. Zeman
doaj   +1 more source