Results 41 to 50 of about 3,043 (170)

The agrin gene codes for a family of basal lamina proteins that differ in function and distribution [PDF]

open access: yes, 1992
We isolated two cDNAs that encode isoforms of agrin, the basal lamina protein that mediates the motor neuron-induced aggregation of acetylcholine receptors on muscle fibers at the neuromuscular junction.
Tsim, K. W.   +13 more
core   +1 more source

Biphasic effect of pentobarbitone on chick myotube nicotinic receptor channel kinetics [PDF]

open access: yesBritish Journal of Pharmacology, 1996
The modulatory action of pentobarbitone on chick myotube nicotinic acetylcholine receptor kinetics was studied by the patch clamp technique, particularly focussing on effects at low concentrations. Open time sojourn distributions of foetal‐type receptors recorded at room temperature (22–24°C) in cell‐attached mode in the presence of 0.2 μm ...
G J, Liu, B W, Madsen
openaire   +2 more sources

Effects of Serum Deprivation on Myofibrillar Proteolysis in Chick Myotube Cultures

open access: yesBioscience, Biotechnology, and Biochemistry, 2003
We examined the effects of serum deprivation on myofibrillar proteolysis in chick myotubes. Myotubes were incubated with serum-free medium for 24 hours. N(tau)-methylhistidine release, as an index of myofibrillar proteolysis, as well as protease activities such as calpain, proteasome, and cathepsins (B+L and D) activities were increased by serum ...
NAKASHIMA, Kazuki   +2 more
openaire   +2 more sources

The differentiation of chick embryonic myoblasts in primary culture [PDF]

open access: yes, 1991
The differentiation of chick embryonic skeletal myoblasts results in the formation of myotubes which are the precursors of muscle fibres. The fusion of mononucleated myoblasts represents an apparent switching point in differentiation since it results in ...
Evans, Caroline Akrill
core   +1 more source

Enhanced chemosensitivity of chick parasympathetic neurones in co‐culture with myotubes.

open access: yesThe Journal of Physiology, 1982
1. The influence of target interaction upon the electrophysiological properties of dissociated ciliary ganglion cells was investigated by testing the sensitivity of the neuronal somal membrane to ionophoretically applied acetylcholine (ACh). Variations in the percentage of cells responsive to the transmitter were measured with time in culture.
G, Crean, G, Pilar, J B, Tuttle, K, Vaca
openaire   +3 more sources

Purification and characterization of a polypeptide from chick brain that promotes the accumulation of acetylcholine receptors in chick myotubes. [PDF]

open access: yesThe Journal of cell biology, 1986
Acetylcholine receptors (AChRs) are packed in the postsynaptic membrane at neuromuscular junctions at a density of approximately 20,000/micron 2, whereas the density a few micrometers away is less than 20/micron 2. To understand how this remarkable distribution comes about during nerve-muscle synapse formation, we have attempted to isolate factors from
T B, Usdin, G D, Fischbach
openaire   +2 more sources

Effects of Serum Deprivation on Expression of Proteolytic-Related Genes in Chick Myotube Cultures [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 2005
We previously reported that serum deprivation stimulates myofibrillar proteolysis in chick myotubes. In the present study, we examined the effect of serum deprivation on expression of the proteolytic-related genes (ubiquitin, proteasome, calpains, and cathepsin B) by real-time PCR of cDNA in chick myotubes.
NAKASHIMA, Kazuki   +2 more
openaire   +2 more sources

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner   +14 more
wiley   +1 more source

Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications

open access: yesExploration, Volume 6, Issue 2, April 2026.
Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu   +8 more
wiley   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

open access: yesAdvanced Materials, Volume 38, Issue 7, 2 February 2026.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy