The Journal of Poultry Science, 2017 The expression of atrogin-1/MAFbx, a muscle-specific E3 ubiquitin ligase, is increased in catabolic conditions that result in muscle atrophy. The expression of atrogin-1/MAFbx mRNA is also decreased by the insulin-like growth factor-I (IGF-I) in ...
Kazuki Nakashima +4 more
doaj +1 more source
An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix. [PDF]
, 1995 Agrin is an extracellular matrix (ECM) protein with a calculated relative molecular mass of more than 200 kD that induces the aggregation of acetylcholine receptors (AChRs) at the neuromuscular junction. This activity has been mapped to its COOH terminus.
Ruegg, M. A. +11 more
core +1 more source
Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis [PDF]
, 1997 The characteristic shapes and positions of each individual body muscle are established during the process of muscle morphogenesis in response to patterning information from the surrounding mesenchyme. Throughout muscle morphogenesis, primary myotubes are
Arber, S. +5 more
core +1 more source
Agrin binds to the nerve-muscle basal lamina via laminin. [PDF]
, 1997 Agrin is a heparan sulfate proteoglycan that is required for the formation and maintenance of neuromuscular junctions. During development, agrin is secreted from motor neurons to trigger the local aggregation of acetylcholine receptors (AChRs) and other ...
Brandenberger, R +14 more
core +1 more source
The regenerative plasticity of isolated urodele myofibers and its dependence on Msx1 [PDF]
, 2004 The conversion of multinucleate postmitotic muscle fibers to dividing mononucleate progeny cells (cellularisation) occurs during limb regeneration in salamanders, but the cellular events and molecular regulation underlying this remarkable process are not
Brockes, J.P. +21 more
core +2 more sources
Myofibrillar Proteolysis in Chick Myotubes during Oxidative Stress
Journal of Nutritional Science and Vitaminology, 2004 Changes in protein conformation and proteolysis in chick myotubes in response to the induction of oxidative stress by H2O2 treatment were studied. Myotubes were treated for 1 h with H2O2. After this treatment, the H2O2 was removed and the cells were cultured in serum-free medium for 6 and 24 h.
NAKASHIMA, Kazuki +2 more
openaire +3 more sources
Cysteine Suppresses Oxidative Stress-Induced Myofibrillar Proteolysis in Chick Myotubes [PDF]
Bioscience, Biotechnology, and Biochemistry, 2004 The effects of cysteine as an antioxidant nutrient on change in protein modification and myofibrillar proteolysis in chick myotubes by induction of oxidative stress by H(2)O(2) treatment were investigated. Myotubes were treated for 1 h with H(2)O(2) (1 mM).
NAKASHIMA, Kazuki +3 more
openaire +2 more sources
Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site. [PDF]
, 1995 Agrin is a basal lamina protein that induces aggregation of acetylcholine receptors (AChRs) and other molecules at the developing neuromuscular junction.
Ruegg, M. A. +8 more
core +1 more source
Differences in the expression and distribution of flotillin-2 in chick, mice and human muscle cells.
PLoS ONE, 2014 Myoblasts undergo a series of changes in the composition and dynamics of their plasma membranes during the initial steps of skeletal muscle differentiation.
Ana Claudia Batista Possidonio +7 more
doaj +1 more source
On the mechanism of acetylcholine receptor accumulation at newly formed synapses on chick myotubes [PDF]
The Journal of Neuroscience, 1985 We have examined the specificity and the mechanism of acetylcholine receptor (AChR) accumulation at embryonic chick nerve-muscle contacts that form in culture. Spinal cord motoneurons were identified in vitro after labeling them in vivo with Lucifer Yellow-wheat germ agglutinin conjugates.
L W, Role +3 more
openaire +2 more sources