Results 11 to 20 of about 5,774 (182)

Formation of acetylcholine receptor clusters in chick myotubes: migration or new insertion? [PDF]

open access: yesJournal of Cell Biology, 1989
Experiments were performed to study the feasibility of two mechanisms of acetylcholine receptor (ACHR) accumulation in chick myotubes: diffusion and trapping of previously dispersed surface receptors and localized insertion of new receptors at accumulation sites.
Janet Dubinsky
exaly   +3 more sources

Increased K+ inhibits spontaneous contractions reduces myosin accumulation in cultured chick myotubes. [PDF]

open access: yesJournal of Cell Biology, 1982
Increasing the K+ from 5.4 mM to 12 mM in the culture medium of developing chick myotubes causes an immediate cessation of spontaneous contractions and leads to an inhibition of myosin accumulation. The synthesis of myosin continues at the same rate in 12 mM K+ as in 5.4 mM K+ as measured by [3H]leucine incorporation into myosin corrected for ...
E, Bandman, R C, Strohman
exaly   +3 more sources

The Role of Embryonic Chick Muscle Cell Culture in the Study of Skeletal Myogenesis

open access: yesFrontiers in Physiology, 2021
The mechanisms involved in the development of skeletal muscle fibers have been studied in the last 70 years and yet many aspects of this process are still not completely understood.
Manoel L. Costa   +3 more
doaj   +1 more source

AMP-activated Protein Kinase Activation Suppresses Protein Synthesis and mTORC1 Signaling in Chick Myotube Cultures

open access: yesThe Journal of Poultry Science, 2022
Protein synthesis in skeletal muscle is considered one of the most energy-consuming cellular processes. AMP-activated protein kinase (AMPK) is a metabolic master switch that regulates glucose and lipid metabolism, and it is implicated in protein ...
Kazuki Nakashima, Aiko Ishida
doaj   +1 more source

Myotube heterogeneity in developing chick craniofacial skeletal muscles [PDF]

open access: yesDevelopmental Dynamics, 1999
Avian skeletal muscles consist of myotubes that can be categorized according to contraction and fatigue properties, which are based largely on the types of myosins and metabolic enzymes present in the cells. Most mature muscles in the head are mixed, but they display a variety of ratios and distributions of fast and slow muscle cells.
R S, Marcucio, D M, Noden
openaire   +2 more sources

Transport and Secretion of the Wnt3 Ligand by Motor Neuron-like Cells and Developing Motor Neurons

open access: yesBiomolecules, 2021
The vertebrate neuromuscular junction (NMJ) is formed by a presynaptic motor nerve terminal and a postsynaptic muscle specialization. Cumulative evidence reveals that Wnt ligands secreted by the nerve terminal control crucial steps of NMJ synaptogenesis.
Cristina Pinto   +6 more
doaj   +1 more source

Characterization of Gelatin Hydrogels Cross-Linked with Microbial Transglutaminase as Engineered Skeletal Muscle Substrates

open access: yesBioengineering, 2021
Engineered in vitro models of skeletal muscle are essential for efficiently screening drug safety and efficacy. However, conventional culture substrates poorly replicate physical features of native muscle and do not support long-term culture, which ...
Divya Gupta   +2 more
doaj   +1 more source

Reduced PGC-1β protein expression may underlie corticosterone inhibition of mitochondrial biogenesis and oxidative phosphorylation in chicken muscles

open access: yesFrontiers in Physiology, 2022
To uncover the molecular mechanism underlying glucocorticoid-induced loss of mitochondrial integrity in skeletal muscles, studies were performed to investigate whether the peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)-mediated ...
Sheng Li   +6 more
doaj   +1 more source

Regulation of Autophagy in Chick Skeletal Muscle: Effect of mTOR Inhibition

open access: yesThe Journal of Poultry Science, 2020
Autophagy in the skeletal muscle increases under catabolic conditions resulting in muscle atrophy. This study investigated the effect of inhibition of mechanistic target of rapamycin (mTOR) on autophagy in chick skeletal muscle.
Kazuki Nakashima, Aiko Ishida
doaj   +1 more source

The role of Na+/K+-ATPase during chick skeletal myogenesis. [PDF]

open access: yesPLoS ONE, 2015
The formation of a vertebrate skeletal muscle fiber involves a series of sequential and interdependent events that occurs during embryogenesis. One of these events is myoblast fusion which has been widely studied, yet not completely understood.
Taissa Neustadt Oliveira   +6 more
doaj   +1 more source

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