Results 11 to 20 of about 65,110 (168)
Electrophysiological properties of the membrane and acetylcholine receptor in developing rat and chick myotubes. [PDF]
Membrane properties of rat and chick myotubes in various stages of development were studied. Resting membrane potentials (Em) increased from -8 to -55 mV in both rat and chick as the myotubes developed from myoblasts to large multinucleated fibers.
A K, Ritchie, D M, Fambrough
exaly +3 more sources
Evidence that coated vesicles transport acetylcholine receptors to the surface membrane of chick myotubes. [PDF]
Coated vesicles are present in the myoplasm of embryonic chick myotubes grown in vitro. They are most numerous beneath regions of the surface membrane that contain a high density of acetylcholine receptors (AChR). Prolonged exposure of myotubes to saline extract of chick brain increases the number of intracellular AChR and the number of coated vesicles.
S, Bursztajn, G D, Fischbach
exaly +3 more sources
The Role of Embryonic Chick Muscle Cell Culture in the Study of Skeletal Myogenesis
The mechanisms involved in the development of skeletal muscle fibers have been studied in the last 70 years and yet many aspects of this process are still not completely understood.
Manoel L. Costa +3 more
doaj +1 more source
Protein synthesis in skeletal muscle is considered one of the most energy-consuming cellular processes. AMP-activated protein kinase (AMPK) is a metabolic master switch that regulates glucose and lipid metabolism, and it is implicated in protein ...
Kazuki Nakashima, Aiko Ishida
doaj +1 more source
Myotube heterogeneity in developing chick craniofacial skeletal muscles [PDF]
Avian skeletal muscles consist of myotubes that can be categorized according to contraction and fatigue properties, which are based largely on the types of myosins and metabolic enzymes present in the cells. Most mature muscles in the head are mixed, but they display a variety of ratios and distributions of fast and slow muscle cells.
R S, Marcucio, D M, Noden
openaire +2 more sources
Transport and Secretion of the Wnt3 Ligand by Motor Neuron-like Cells and Developing Motor Neurons
The vertebrate neuromuscular junction (NMJ) is formed by a presynaptic motor nerve terminal and a postsynaptic muscle specialization. Cumulative evidence reveals that Wnt ligands secreted by the nerve terminal control crucial steps of NMJ synaptogenesis.
Cristina Pinto +6 more
doaj +1 more source
Engineered in vitro models of skeletal muscle are essential for efficiently screening drug safety and efficacy. However, conventional culture substrates poorly replicate physical features of native muscle and do not support long-term culture, which ...
Divya Gupta +2 more
doaj +1 more source
To uncover the molecular mechanism underlying glucocorticoid-induced loss of mitochondrial integrity in skeletal muscles, studies were performed to investigate whether the peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)-mediated ...
Sheng Li +6 more
doaj +1 more source
Regulation of Autophagy in Chick Skeletal Muscle: Effect of mTOR Inhibition
Autophagy in the skeletal muscle increases under catabolic conditions resulting in muscle atrophy. This study investigated the effect of inhibition of mechanistic target of rapamycin (mTOR) on autophagy in chick skeletal muscle.
Kazuki Nakashima, Aiko Ishida
doaj +1 more source
The role of Na+/K+-ATPase during chick skeletal myogenesis. [PDF]
The formation of a vertebrate skeletal muscle fiber involves a series of sequential and interdependent events that occurs during embryogenesis. One of these events is myoblast fusion which has been widely studied, yet not completely understood.
Taissa Neustadt Oliveira +6 more
doaj +1 more source

