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Chikungunya fever

Nature Reviews Disease Primers, 2023
Chikungunya virus is widespread throughout the tropics, where it causes recurrent outbreaks of chikungunya fever. In recent years, outbreaks have afflicted populations in East and Central Africa, South America and Southeast Asia. The virus is transmitted by Aedes aegypti and Aedes albopictus mosquitoes.
Kathryn E Stephenson, Lisa Ng, Kevin K Ariën   +2 more
exaly   +5 more sources

In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses

Frontiers in Cellular and Infection Microbiology, 2022
Dengue and chikungunya are two important mosquito-borne infections which are known to occur extensively in tropical and subtropical areas. Presently, there is no treatment for these viral diseases.
Kalichamy Alagarasu, Poonam Patil, Meenakshi Kaushik, Deepika Chowdhury, Rajesh K. Joshi, Harsha V. Hegde, Mahadeo B. Kakade, Sugeerappa Laxmanappa Hoti, Sarah Cherian, Deepti Parashar   +9 more
doaj   +2 more sources

Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples

Nature Biomedical Engineering, 2022
In low-resource settings, resilience to infectious disease outbreaks can be hindered by limited access to diagnostic tests. Here we report the results of double-blinded studies of the performance of paper-based diagnostic tests for the Zika and ...
Severino Jefferson Ribeiro da Silva, Andrea Denisse Benitez Quintana, Darius G Rackus   +2 more
exaly   +2 more sources

Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

Viruses, 2022
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by the sudden onset of symptoms, including fever, rash, myalgia, and headache.
Mohamad S. Hakim, Abu T. Aman
doaj   +2 more sources

The global health and economic burden of chikungunya from 2011 to 2020: a model-driven analysis on the impact of an emerging vector-borne disease

BMJ Global Health
Introduction Chikungunya is a mosquito-borne arboviral disease posing an emerging global public health threat. Understanding the global burden of chikungunya is critical for designing effective prevention and control strategies.
Adrianne Marije de Roo, Gerard Timmy Vondeling, Martijn Boer, Kristy Murray, Maarten Jacobus Postma   +4 more
doaj   +2 more sources

Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models

PLoS Neglected Tropical Diseases, 2017
Recent epidemics of Zika, dengue, and chikungunya have heightened the need to understand the seasonal and geographic range of transmission by Aedes aegypti and Ae. albopictus mosquitoes.
Erin A Mordecai, Jeremy M Cohen, Michelle V Evans   +2 more
exaly   +2 more sources

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

Science Immunology, 2019
Lipid nanoparticles containing mRNA encoding a human antibody for chikungunya virus protect against infection and arthritis. mRNA-based passive immunotherapy Passive transfer of neutralizing antibodies can protect against disease caused by chikungunya ...
Nurgun Kose, Julie M Fox, Gopal Sapparapu   +2 more
exaly   +2 more sources

Performance of the Trioplex real-time RT-PCR assay for detection of Zika, dengue, and chikungunya viruses

Nature Communications, 2018
The emergence and spread of Zika virus (ZIKV) presented a challenge to the diagnosis of ZIKV infections in areas with transmission of dengue (DENV) and chikungunya (CHIKV) viruses.
G. Santiago, Jesús Vázquez, S. Courtney, Katia Y. Matías, Lauren E. Andersen, Candimar Colón, A. Butler, Rebecca M. Roulo, John Bowzard, Julie M. Villanueva, J. Muñoz-Jordán   +10 more
exaly   +2 more sources

Zika, Chikungunya, and Other Emerging Vector-Borne Viral Diseases

Annual Review of Medicine, 2018
Scott C Weaver, Caroline Charlier, Nikos Vasilakis   +2 more
exaly   +2 more sources

Seroprevalence of dengue virus infection in Pune City in India, 2019: A decadal change

Journal of Infection and Public Health, 2023
Background: The burden of dengue infection needs to be monitored along with tracking of the changes in dengue virus (DENV) transmission intensity for vaccine introduction decisions.
Kalichamy Alagarasu, Shilpa Tomar, Jayashri Patil, Rupali Bachal, Reva More, Minal Bote, Mahadeo Kakade, Vasanthy Venkatesh, Deepti Parashar, Babasaheb V. Tandale   +9 more
doaj   +1 more source