Results 1 to 10 of about 99,250 (279)

In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses

Frontiers in Cellular and Infection Microbiology, 2022
Dengue and chikungunya are two important mosquito-borne infections which are known to occur extensively in tropical and subtropical areas. Presently, there is no treatment for these viral diseases.
Kalichamy Alagarasu, Poonam Patil, Meenakshi Kaushik, Deepika Chowdhury, Rajesh K. Joshi, Harsha V. Hegde, Mahadeo B. Kakade, Sugeerappa Laxmanappa Hoti, Sarah Cherian, Deepti Parashar   +9 more
doaj   +2 more sources

The global epidemiology of chikungunya from 1999 to 2020: A systematic literature review to inform the development and introduction of vaccines

PLoS Neglected Tropical Diseases, 2022
Chikungunya fever is an acute febrile illness that is often associated with severe polyarthralgia in humans. The disease is caused by chikungunya virus (CHIKV), a mosquito-borne alphavirus.
Alison A. Bettis, Maïna L’Azou, In-Kyu Yoon, J. Gabrielle Breugelmans, Ana Goios, Duane J. Gubler, Ann M. Powers   +6 more
openalex   +2 more sources

Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples

Nature Biomedical Engineering, 2022
In low-resource settings, resilience to infectious disease outbreaks can be hindered by limited access to diagnostic tests. Here we report the results of double-blinded studies of the performance of paper-based diagnostic tests for the Zika and ...
Severino Jefferson Ribeiro da Silva, Andrea Denisse Benitez Quintana, Darius G Rackus   +2 more
exaly   +2 more sources

Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

Viruses, 2022
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by the sudden onset of symptoms, including fever, rash, myalgia, and headache.
Mohamad S. Hakim, Abu T. Aman
doaj   +2 more sources

The global health and economic burden of chikungunya from 2011 to 2020: a model-driven analysis on the impact of an emerging vector-borne disease

BMJ Global Health
Introduction Chikungunya is a mosquito-borne arboviral disease posing an emerging global public health threat. Understanding the global burden of chikungunya is critical for designing effective prevention and control strategies.
Adrianne Marije de Roo, Gerard Timmy Vondeling, Martijn Boer, Kristy Murray, Maarten Jacobus Postma   +4 more
doaj   +2 more sources

Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models

PLoS Neglected Tropical Diseases, 2017
Recent epidemics of Zika, dengue, and chikungunya have heightened the need to understand the seasonal and geographic range of transmission by Aedes aegypti and Ae. albopictus mosquitoes.
Erin A Mordecai, Jeremy M Cohen, Michelle V Evans   +2 more
exaly   +2 more sources

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

Science Immunology, 2019
Lipid nanoparticles containing mRNA encoding a human antibody for chikungunya virus protect against infection and arthritis. mRNA-based passive immunotherapy Passive transfer of neutralizing antibodies can protect against disease caused by chikungunya ...
Nurgun Kose, Julie M Fox, Gopal Sapparapu   +2 more
exaly   +2 more sources

Chikungunya fever

Nature Reviews Disease Primers, 2023
Kathryn E Stephenson, Lisa Ng, Kevin K Ariën   +2 more
exaly   +2 more sources

A case series of neuro-chikungunya: unmasking the neurotropic potential of chikungunya virus. [PDF]

BMC Infect Dis
Supanchana P, Kirushanth C, Wijewardana CT, Peiris LT, Jayasinghe J, Rudra A, Govindapala D, Higgoda R, Thivakaran T, Muthugala R, Perera N, Manilgama S.   +11 more
europepmc   +2 more sources

Age-specific chikungunya outbreak response immunisation strategies in Brazil: a modelling study. [PDF]

EClinicalMedicine
Kang H, Lim A, Clark A, Colón González FJ, Clapham HE, Carrera JP, Kim JH, Auzenbergs M, Lakshminarayanan P, López-Vergès S, Sim SY, Han SM, Cerqueira-Silva T, Endy T, Cucunubá ZM, Edmunds WJ, Sahastrabuddhe S, Brady OJ, Abbas K.   +18 more
europepmc   +2 more sources