Results 21 to 30 of about 55,640 (226)

Drug repurposing approach against chikungunya virus: an in vitro and in silico study

Frontiers in Cellular and Infection Microbiology, 2023
The chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes. There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing approach has emerged as a novel concept to find alternative uses of therapeutics to
Bhagyashri Kasabe, Gunwant Ahire, Poonam Patil, Madhura Punekar, Kusuma Sai Davuluri, Mahadeo Kakade, Kalichamy Alagarasu, Deepti Parashar, Sarah Cherian   +8 more
doaj   +1 more source

Targeted in vitro gene silencing of E2 and nsP1 genes of chikungunya virus by biocompatible zeolitic imidazolate framework

Frontiers in Bioengineering and Biotechnology, 2022
Chikungunya fever caused by the mosquito-transmitted chikungunya virus (CHIKV) is a major public health concern in tropical, sub-tropical and temperate climatic regions.
Rajarshee Tagore, Kalichamy Alagarasu, Poonam Patil, Suneela Pyreddy, Suneela Pyreddy, Shakil Ahmed Polash, Shakil Ahmed Polash, Mahadeo Kakade, Ravi Shukla, Ravi Shukla, Deepti Parashar   +10 more
doaj   +1 more source

Serotype and genotype diversity of dengue viruses circulating in India: a multi-centre retrospective study involving the Virus Research Diagnostic Laboratory Network in 2018

International Journal of Infectious Diseases, 2021
: Objectives: A retrospective study was undertaken to investigate the circulating dengue virus (DENV) serotypes and genotypes in India in 2018. Methods: In total, 4963 samples referred to virus research diagnostic laboratories (n=21), the Indian Council
K. Alagarasu, J.A. Patil, M.B. Kakade, A.M. More, B. Yogesh, P. Newase, S.M. Jadhav, D. Parashar, H. Kaur, N. Gupta, N. Vijay, J. Narayan, P.S. Shah, Dr Ajanta Sharma, Dr Amita Jain, Dr Anudita Bhargava, Dr B. Anukumar, Dr Ashok M, Dr Bharti Malhotra, Dr B.J. Borkakoty, Dr Debasis Biswas, Dr SC Jaryal, Dr Kanwardeep Singh Dhingra, Dr K. Kaveri, Dr P.K. Khatri, Dr Manoj Kumar, Dr K. Nagamani, Dr Rahul Dhodapkar, Dr Rupinder Bakshi, Dr Paramjeet S. Gill, Dr Sanghamitra Pati, Dr Shanta Dutta, Dr Shantala G, Dr Usha Kalawat, Dr Disha A. Patel, Dr P. Vijayachari   +35 more
doaj   +1 more source

In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses

Frontiers in Cellular and Infection Microbiology, 2022
Dengue and chikungunya are two important mosquito-borne infections which are known to occur extensively in tropical and subtropical areas. Presently, there is no treatment for these viral diseases.
Kalichamy Alagarasu, Poonam Patil, Meenakshi Kaushik, Deepika Chowdhury, Rajesh K. Joshi, Harsha V. Hegde, Mahadeo B. Kakade, Sugeerappa Laxmanappa Hoti, Sarah Cherian, Deepti Parashar   +9 more
doaj   +1 more source

An Update on Current Antiviral Strategies to Combat Human Cytomegalovirus Infection

Viruses, 2023
Human cytomegalovirus (HCMV) remains an essential global concern due to its distinct life cycle, mutations and latency. As HCMV is a herpesvirus, it establishes a lifelong persistence in the host through a chronic state of infection.
Kingshuk Panda, Deepti Parashar, Rajlakshmi Viswanathan   +2 more
doaj   +1 more source

Dengue- und Chikungunya-Fieber in der Allgemeinpraxis [PDF]

, 2009
Quintessenz: Dengue und Chikungunya sind akute Viruserkrankungen mit hohem Fieber, Kopfschmerzen, Gliederschmerzen, Hautausschlägen, welche in zahlreichen Ländern des Südens sehr verbreitet sind und auch Touristen betreffen.
Blum, J., Hatz, C. F., Hatz, C, Blum, J
core   +1 more source

Studies on the antiviral activity of chebulinic acid against dengue and chikungunya viruses and in silico investigation of its mechanism of inhibition

Scientific Reports, 2022
Chebulinic acid (CA), originally isolated from the flower extract of the plant Terminalia chebula, has been shown to inhibit infection of herpes simplex virus-2 (HSV-2), suggestively by inhibiting the host entry step of viral infection.
Naiju Thomas, Poonam Patil, Anjana Sharma, Sandeep Kumar, Vikas Kumar Singh, Kalichamy Alagarasu, Deepti Parashar, Suman Tapryal   +7 more
doaj   +1 more source

Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

Viruses, 2022
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by the sudden onset of symptoms, including fever, rash, myalgia, and headache.
Mohamad S. Hakim, Abu T. Aman
doaj   +1 more source

Pan-European Chikungunya surveillance: Designing risk stratified surveillance zones [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Tilston et alThe first documented transmission of Chikungunya within Europe took place in Italy during the summer of 2007.
Skelly, C., Tilston, N., Tilston, Natasha, Chris Skelly, Phil Weinstein, Weinstein, P, Weinstein, Phil, Weinstein, P., Tilston Natasha, Weinstein Phil, Tilston, N, Skelly Chris, Skelly, C, Skelly, Chris, Natasha Tilston   +14 more
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Seroprevalence and incidence of primary dengue infections among children in a rural region of Maharashtra, Western India

BMC Infectious Diseases, 2019
Background Dengue infections have become a huge threat to public health systems in developing countries. Data on seroprevalence and incidence of dengue infections are lacking from rural regions of India.
Paresh S. Shah, Kalichamy Alagarasu, Shivaji Karad, Avinash Deoshatwar, Santosh M. Jadhav, Tushar Raut, Anand Singh, Cecilia Dayaraj, Vasant S. Padbidri   +8 more
doaj   +1 more source