Results 31 to 40 of about 84,186 (256)

Evidence of chikungunya virus infections among febrile patients at three secondary health facilities in the Ashanti and the Bono Regions of Ghana.

PLoS Neglected Tropical Diseases, 2021
BackgroundChikungunya is now of public health concern globally due to its re-emergence in endemic areas and introduction into new areas of the world.
Jonathan Akwasi Adusei, Patrick Williams Narkwa, Michael Owusu, Seth Agyei Domfeh, Mahmood Alhassan, Emmanuel Appau, Alimatu Salam, Mohamed Mutocheluh   +7 more
doaj   +1 more source

Chikungunya Virus

Clinics in Laboratory Medicine, 2017
For chikungunya virus (CHIKV), the long-term sequelae from infection are yet ill-defined. The prolonged debilitating arthralgia associated with CHIKV infection has tremendous potential for impacting the global economy and should be considered when evaluating the human burden of disease and the allocation of resources.
Vu, David M., Jungkind, Donald, Angelle Desiree LaBeaud   +2 more
openaire   +2 more sources

Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia

Tropical Medicine and Infectious Disease, 2022
Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks.
Marsha Sinditia Santoso, Sotianingsih Haryanto, Fadil Rulian, Rahma F. Hayati, Amanda Kristiani, Rini Kartika, Benediktus Yohan, Martin L. Hibberd, R. Tedjo Sasmono   +8 more
doaj   +1 more source

Explorations on the antiviral potential of zinc and magnesium salts against chikungunya virus: implications for therapeutics

Frontiers in Cellular and Infection Microbiology
BackgroundChikungunya virus (CHIKV), which causes chikungunya fever, is an arbovirus of public health concern with no approved antiviral therapies. A significant proportion of patients develop chronic arthritis after an infection.
Kusuma Sai Davuluri, Shridhar Shukla, Mahadeo Kakade, Sarah Cherian, Sarah Cherian, Kalichamy Alagarasu, Kalichamy Alagarasu, Deepti Parashar, Deepti Parashar   +8 more
doaj   +1 more source

Chikungunya

Clinics in Laboratory Medicine, 2010
Chikungunya virus is a zoonotic, vector-borne pathogen that has been responsible for numerous outbreaks of febrile arthralgia since its discovery in the early 1950s. In the past decade, the virus has re-emerged more frequently, causing massive epidemics that have moved from Africa throughout the Indian Ocean to India and Southeast Asia. A discussion of
openaire   +5 more sources

The interferon-induced exonuclease ISG20 exerts antiviral activity through upregulation of type I interferon response proteins [PDF]

, 2018
The host immune responses to infection lead to the production of type I interferon (IFN), and the upregulation of interferon-stimulated genes (ISGs) reduces virus replication and virus dissemination within a host.
Diamond, Michael S, Klimstra, William B, Lucas, Tiffany M, Ryman, Kate D, Sun, Chengqun, Trobaugh, Derek W, Weiss, Christopher M   +6 more
core   +2 more sources

Durability of Functional SARS-CoV-2-Specific Immunological Memory and T Cell Response up to 8–9 Months Postrecovery From COVID-19

Journal of Immunology Research
Research on long-term follow-up in individuals who have recovered from coronavirus disease-19 (COVID-19) would yield insights regarding their immunity status and identify those who need booster vaccinations.
Diptee Trimbake, Dharmendra Singh, Yogesh Gurav K., Prasad Babar, Varsha Dange S., Anuradha S. Tripathy   +5 more
doaj   +1 more source

RNAi-Induced Gene Silencing against Chikungunya and COVID-19: What Have We Learned So Far, and What Is the Way Forward?

Viruses
RNA interference (RNAi) is a process in which small RNA molecules (such as small interfering RNAs or siRNAs) bind to specific messenger RNAs (mRNAs), leading to its degradation and inhibition of protein synthesis.
Kingshuk Panda, Kalichamy Alagarasu, Rajarshee Tagore, Mandar Paingankar, Satyendra Kumar, Manish Kumar Jeengar, Sarah Cherian, Deepti Parashar   +7 more
doaj   +1 more source

Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective

Scientific Reports, 2023
The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate.
Tao-Qian Tang, Rashid Jan, Adil Khurshaid, Zahir Shah, Narcisa Vrinceanu, Mihaela Racheriu   +5 more
doaj   +1 more source

A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]

, 2016
Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano, Bracher, Franz, Braun, Peter, Couderc, Thérèsr, Gangneux, Nicolas, Karlas, Alexander, Karo-Astover, Liis, Klemm, Uwe, Lecuit, Marc, Merits, Andres, Meyer, Michael, Meyer, Thomas F., Raftery, Martin, Schönrich, Günther, Varjak, Margus, Weege, Friderike, Wurzlbauer, Anne   +16 more
core   +5 more sources