Results 31 to 40 of about 49,500 (227)

Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia

Tropical Medicine and Infectious Disease, 2022
Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks.
Marsha Sinditia Santoso, Sotianingsih Haryanto, Fadil Rulian, Rahma F. Hayati, Amanda Kristiani, Rini Kartika, Benediktus Yohan, Martin L. Hibberd, R. Tedjo Sasmono   +8 more
doaj   +1 more source

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling [PDF]

, 2010
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected ...
Ligtenberg, M., Suhrbier, A., Corinne Geertsema, Esther Schnettler, Fros, J., Just M. Vlak, Maarten Ligtenberg, Geertsema, C., Suhrbier, Andreas, Wen Jun Liu, Natalie A. Prow, Vlak, J.M., Dana L. Vanlandingham, Ligtenberg, Maarten, Khromykh, Alexander A., Jelke J. Fros, Vanlandingham, D.L., Vlak, Just M., Schnettler, E., Fros, J.J., Gorben P. Pijlman, Pijlman, G.P., Liu, W.J., Khromykh, A.A., Prow, A., Fros, Jelke J., Vanlandingham, Dana L., Liu, Wen Jun, Geertsema, Corinne, Prow, Natalie A., Alexander A. Khromykh, Schnettler, Esther, Pijlman, Gorben P., Andreas Suhrbier, Prow, N.A.   +34 more
core   +1 more source

Explorations on the antiviral potential of zinc and magnesium salts against chikungunya virus: implications for therapeutics

Frontiers in Cellular and Infection Microbiology
BackgroundChikungunya virus (CHIKV), which causes chikungunya fever, is an arbovirus of public health concern with no approved antiviral therapies. A significant proportion of patients develop chronic arthritis after an infection.
Kusuma Sai Davuluri, Shridhar Shukla, Mahadeo Kakade, Sarah Cherian, Sarah Cherian, Kalichamy Alagarasu, Kalichamy Alagarasu, Deepti Parashar, Deepti Parashar   +8 more
doaj   +1 more source

Chikungunya: an overview

Journal of Biosciences, 2008
Chikungunya (CHIK),a mosquito borne debilitating disease,is caused by CHIK virus,an alphavirus belonging to the family Togaviridae.The sudden onset of very high fever along with rash, and severe arthralgia especially in the small joints of hands and toes are the characteristics of the disease.
A B, Sudeep, D, Parashar
openaire   +2 more sources

Genetic predisposition to chikungunya – a blood group study in chikungunya affected families

Virology Journal, 2009
Chikungunya fever is a viral disease transmitted to humans by the bite of CHIKV virus infected Aedes mosquitoes. During monsoon outbreak of chikungunya fever, we carried out the genetic predisposition to chikungunya in disease affected 100 families by ...
Ramakrishna Vadde, Sarojamma Vemula, Sudarsanareddy Lokireddy   +2 more
doaj   +1 more source

Increased Indoleamine 2,3-Dioxygenase 1 (IDO-1) Activity and Inflammatory Responses during Chikungunya Virus Infection

Pathogens, 2022
Chikungunya virus (CHIKV) infection causes intense cytokine/chemokine inflammatory responses and debilitating joint pain. Indoleamine2,3–dioxygenase 1 (IDO-1) is an enzyme that initiates the tryptophan degradation that is important in initial host innate
Thiara Manuele Alves de Souza, Caroline Fernandes-Santos, Jéssica Araújo da Paixão de Oliveira, Larissa Cristina Teixeira Tomé, Victor Edgar Fiestas-Solórzano, Priscila Conrado Guerra Nunes, Gabriel Macedo Costa Guimaraes, Juan Camilo Sánchez-Arcila, Iury Amâncio Paiva, Luís Jose de Souza, Paulo Vieira Damasco, Válber da Silva Frutuoso, Manoela Heringer, Luzia Maria de Oliveira-Pinto, Roberta Olmo Pinheiro, Flavia Barreto dos Santos, Elzinandes Leal de Azeredo   +16 more
doaj   +1 more source

Estimating drivers of autochthonous transmission of Chikungunya virus in its invasion of the Americas

, 2015
Background: Chikungunya is an emerging arbovirus that has caused explosive outbreaks in Africa and Asia for decades and invaded the Americas just over a year ago.
Tatem, A.J., Andrew J. Tatem, Perkins, T. Alex, Metcalf, C.J.E., Bryan T. Grenfell, Tatem, Andrew J., C. Jessica E. Metcalf, Metcalf, C. Jessica E., Perkins, T.A., Grenfell, Bryan T., T. Alex Perkins, Grenfell, B.T.   +11 more
core   +1 more source

Durability of Functional SARS-CoV-2-Specific Immunological Memory and T Cell Response up to 8–9 Months Postrecovery From COVID-19

Journal of Immunology Research
Research on long-term follow-up in individuals who have recovered from coronavirus disease-19 (COVID-19) would yield insights regarding their immunity status and identify those who need booster vaccinations.
Diptee Trimbake, Dharmendra Singh, Yogesh Gurav K., Prasad Babar, Varsha Dange S., Anuradha S. Tripathy   +5 more
doaj   +1 more source

RNAi-Induced Gene Silencing against Chikungunya and COVID-19: What Have We Learned So Far, and What Is the Way Forward?

Viruses
RNA interference (RNAi) is a process in which small RNA molecules (such as small interfering RNAs or siRNAs) bind to specific messenger RNAs (mRNAs), leading to its degradation and inhibition of protein synthesis.
Kingshuk Panda, Kalichamy Alagarasu, Rajarshee Tagore, Mandar Paingankar, Satyendra Kumar, Manish Kumar Jeengar, Sarah Cherian, Deepti Parashar   +7 more
doaj   +1 more source

Analysis of the dynamics of a vector-borne infection with the effect of imperfect vaccination from a fractional perspective

Scientific Reports, 2023
The burden of vector-borne infections is significant, particularly in low- and middle-income countries where vector populations are high and healthcare infrastructure may be inadequate.
Tao-Qian Tang, Rashid Jan, Adil Khurshaid, Zahir Shah, Narcisa Vrinceanu, Mihaela Racheriu   +5 more
doaj   +1 more source