Results 91 to 100 of about 7,593,002 (356)
Co-development of child-mother gestures over the second and the third years [PDF]
, 2006 María José Rodrigo López +5 more
openalex +1 more source
VALİDİTY AND RELİABİLİTY STUDY OF CHİLD ABUSE AND NEGLECT AWARENESS SCALES [PDF]
, 2023 Umay Büşra CELİLOĞLU
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Autism spectrum disorders [PDF]
The earlier that children with an Autism Spectrum Disorder (ASD) receive referral, diagnosis and intervention, the better the long-term results are for those children and their families (Barbaro & Dissanyake, 2009; Wiggins et al., 2006; Mandell et al.
Centre for Community Child Health
core
Child and Adolescent Health in Armenia: Experiences and Learned Lessons [PDF]
, 2016 Sergey Sargsyan +3 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
One of the key responsibilities of parents is to help children learn to manage their emotions and behaviour. This supports children to become personally fulfilled individuals who can participate effectively in society.
Centre for Community Child Health
core
Rising to the Challenge: The Strategies of Social Service Intermediaries [PDF]
, 2012 During the past decade, "intermediary organizations" have proliferated across the nonprofit sector. These organizations are typically positioned between funding entities (e.g., government agencies, foundations and corporations) and direct service ...
Child Trends +2 more
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source