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Language outcomes and influencing factors in children with language delay: a retrospective cohort analysis [PDF]

open access: yesScientific Reports
Language delay (LD) is a common developmental issue, but the understanding of its natural language outcomes is still limited. This study tracked the language development outcomes and influencing factors of LD longitudinally, providing a basis for early ...
Lin Zhu   +9 more
doaj   +2 more sources

Outcomes of percutaneous balloon pulmonary valvuloplasty in congenital pulmonary valve stenosis

open access: yesClinical Case Reports, 2021
Percutaneous balloon pulmonary valvuloplasty (PBPV) is the primary treatment for pulmonary valve stenosis (PVS). The study consisted of 228 children with PVS who underwent PBPV from January 2004 to October 2019 at a single center.
Dan Yin   +7 more
doaj   +1 more source

Validation of the children international IgA nephropathy prediction tool based on data in Southwest China

open access: yesFrontiers in Pediatrics, 2023
BackgroundImmunoglobulin A nephropathy (IgAN) is one of the most common kidney diseases leading to renal injury. Of pediatric cases, 25%–30% progress into end-stage kidney disease (ESKD) in 20–25 years. Therefore, predicting and intervening in IgAN at an
Xixi Yu   +11 more
doaj   +1 more source

Childhood ischaemic stroke in the basal ganglia can lead to fine motor and anxiety disorders: a retrospective analysis and follow-up of 109 cases

open access: yesBMC Neurology, 2021
Background Stroke in children easily causes long-term dysfunction. Whether the prognoses of motor and anxiety disorders are related to the affected stroke area has not been reported.
Tianyi Li   +6 more
doaj   +1 more source

Do children with left ventricular noncompaction and a noncompaction-to-compaction ratio < 2 have a better prognosis?

open access: yesBMC Pediatrics, 2020
Background Ultrasonography is commonly used to diagnose left ventricular noncompaction (LVNC). A ratio of noncompacted to compacted myocardium (NC/C ratio) > >2 is often used to diagnose LVNC.
Yi Gan   +4 more
doaj   +1 more source

CCNB1 is a novel prognostic biomarker and promotes proliferation, migration and invasion in Wilms tumor

open access: yesBMC Medical Genomics, 2023
Background Wilms tumour (WT) is a mixed type of embryonal tumour that usually occurs in early childhood. However, our knowledge of the pathogenesis or progression mechanism of WT is inadequate, and there is a scarcity of beneficial therapeutic strategies.
Bin Xiang   +8 more
doaj   +1 more source

Astrocyte-Ablation of Mtnr1b Increases Anxiety-Like Behavior in Adult Male Mice

open access: yesJournal of Integrative Neuroscience, 2023
Background: Astrocytes are essential for synaptic transmission, and their dysfunction can result in neuropsychiatric disorders such as anxiety and depression.
Zijun Meng   +11 more
doaj   +1 more source

Child Sexual Abuse as a Unique Risk Factor for the Development of Psychopathology: The Compounded Convergence of Mechanisms.

open access: yesAnnual Review of Clinical Psychology, 2021
Meta-analytic, population cohort, prospective, and clinical studies provide systematic evidence that child sexual abuse accounts for unique variation in several deleterious outcomes.
Jennie G. Noll
semanticscholar   +1 more source

NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes

open access: yesStem Cell Research & Therapy, 2021
Background Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great promise for regenerative medicine and in drugs screening.
Xinyuan Zhang   +10 more
doaj   +1 more source

Dihydroartemisinin attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting oxidative stress

open access: yesMolecular Brain, 2022
Neonatal hypoxic-ischemic encephalopathy (HIE) induced by perinatal asphyxia is a major cause of neurological disability among infants. Dihydroartemisinin (DHA), derived from artemisinin, well known as an anti-malarial medicine, was proved to be able to ...
Qian Xiong   +5 more
doaj   +1 more source

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