Results 61 to 70 of about 17,977,226 (311)

Total colonic aganglionosis in children: clinical manifestations, diagnosis, treatment and outcome

Di-san junyi daxue xuebao, 2020
Objective To explore the clinical features, diagnosis and treatments of total colonic aganglionosis(TCA) in children. Methods We retrospectively analyzed the clinical data of 41 children with TCA (including 31 boys and 10 girls), who were diagnosed and ...
ZHANG Zhenyu, SUN Jing, HOU Jinping, LIU Qingshuang, LIU Wei, LI Xiaoqing, WANG Yi   +6 more
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Global prevalence of occult hepatitis B virus infection in HBcAb-positive individuals: a systematic review and meta-analysis

Scientific Reports
Many people worldwide test negative for hepatitis B surface antigen (HBsAg) but positive for hepatitis B core antibody (HBcAb), posing potential clinical challenges of occult hepatitis B virus (HBV) infection (OBI), including viral reactivation and ...
Yuting Yang, Huiwu Xing, Guojin Wu, Yao Zhao   +3 more
doaj   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

The Validity of the Screen for Child Anxiety Related Emotional Disorders Revised (SCARED-R) Scale and Sub-Scales in Swedish Youth [PDF]

, 2017
We evaluated the clinical utility of the Swedish SCARED-R in child- and adolescent psychiatric outpatients (n = 239) and validated it against Longitudinal Expert All Data (LEAD) DSM IV diagnoses based on the Children’s Schedule for Affective Disorders ...
Andersson, Markus, Tord Ivarsson, Markus Andersson, Skarphedinsson, Gudmundur, Håkan Jarbin, Ivarsson, Tord, Ivarsson, Tord,, Gudmundur Skarphedinsson, Jarbin, Håkan, Jarbin, Håkan,, Skarphedinsson, Gudmundur,, Andersson, Markus,, Lund University.   +12 more
core   +1 more source

Inverse association between Helicobacter pylori infection and childhood asthma in a physical examination population: a cross-sectional study in Chongqing, China

BMC Pediatrics, 2022
Background Childhood asthma has substantial effects on children's health. It is important to identify factors in early life that influence childhood asthma.
Donghai Wang, Yuxia Chen, Yuan Ding, Jinwei Tu   +3 more
doaj   +1 more source

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Naringenin inhibits phosphorylated protein kinase C-δ and reduces inflammatory injury in rats after intracerebral hemorrhage

Di-san junyi daxue xuebao, 2020
Objective To investigate the effects of naringenin (NGN) on inflammatory injury after intracerebral hemorrhage (ICH) in rats and its possible molecular mechanism.
XIAO Han, ZHANG Li, WANG Lu, CHEN Hui, GAN Hui, GAN Hui, ZHENG Shuyue   +6 more
doaj   +1 more source

Impact of growth hormone on scoliosis

Pediatric Discovery, 2023
Growth hormone (GH) therapy has been used in patients with growth retardation and short stature due to various reasons. The safety of GH treatment is still debatable, one of which is the occurrence and development of scoliosis.
Xin‐Kai Zhang, Xiang Li, Ming‐Yan Shi, Man Zhang, Pei‐Kang Wang, Hai‐Lun Yao, Xin Tan, Xiang Yu, Yu‐Fei Shao, Xing Liu   +9 more
doaj   +1 more source