Results 81 to 90 of about 17,977,226 (311)
Brain and BehaviorObjective This study aims to investigate the alterations in structural and functional connectivity networks (SCN and FCN) in children with hypothalamic syndrome (HS) following craniopharyngioma resection and to explore the relationship between these ...
Shuang Li +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The conundrums of human development – implications for the study of child and adolescent disorder [PDF]
Journal of Child Psychology and Psychiatry, 2017 The conundrums inherent in the study of child and adolescent development are likely never far from the minds of the readers of JCPP . The complexity of development is flagged clearly in this issue.
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Challenging Inequalities: Our Early Childhood Development Sector Framework Document at a Glance
Investing in the first five years of life is essential for early childhood development (ECD) and contributes to increasing societal productivity, reducing poverty, and promoting equality.
Inter-American Development Bank
core +1 more source
Semiology and neurophysiology of clonic seizures in children: a retrospective study
Frontiers in NeurologyObjectivesTo identify and quantify clonic seizures in children, we retrospectively reviewed the clinical symptoms and neurophysiology of them.MethodsData were obtained from 24 patients presenting with 34 clonic seizures, and their video ...
Qiao Hu +5 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The Effect of Maternal Depression and Substance Abuse on Child Human Capital Development [PDF]
Recent models of human capital formation represent a synthesis of the human capital approach and a life cycle view of human development that is grounded in neuroscience (Heckman 2007).
Richard G. Frank, Ellen Meara
core
, 2021 Background: Stunting that occurs during childhood will have an impact on the condition of cognitive development in the future. The purpose of this study is to determine the risk factors that have a direct and indirect effect on the stunting and ...
Yunia Sari, Nunik Ike +1 more
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