Results 101 to 110 of about 3,630,700 (310)
Case Reports in Dermatological MedicineConclusion: Harlequin ichthyosis remains associated with a high mortality rate, especially in resource-limited settings. Contributing factors include inadequate prenatal diagnostic services, restricted access to essential treatments, and insufficient ...
Munanura Turyasiima +9 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Television and early childhood development [PDF]
Mass media play a significant role in most people’s lives, affecting family routines, social interactions, cultural norms, and leisure activities – all of which impact upon contemporary childhood. Television is particularly significant in early childhood;
Centre for Community Child Health
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Overweight and obesity in childhood [PDF]
Overweight/obesity during childhood is a major public health issue with more than 200,000 Australian children between 2-18 years now obese (Booth et al, 2003). It has significant health implications across the life span.
Centre for Community Child Health
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Engaging marginalised and vulnerable families [PDF]
This Policy Brief explores the evidence regarding improving access to services for marginalised and vulnerable families with young children, and how families can best be engaged and supported. Why is this issue important?
Centre for Community Child Health
core
An ecological systems approach to examining risk factors for early childhood overweight: findings from the UK Millennium Cohort Study [PDF]
, 2009 Objective: To use an ecological systems approach to examine individual-, family-, community- and area-level risk factors for overweight (including obesity) in 3-year-old children. Methods: A prospective nationally representative cohort study conducted in
Cole, T.J. +3 more
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source