Results 111 to 120 of about 3,630,700 (310)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Achieving the Millennium Development Goals : The role of infrastructure [PDF]
The authors provide an empirical analysis of the determinants of three child-health outcomes related to the Millennium Development Goals: the infant mortality rate, the child mortality rate, and the prevalence of malnutrition. Using data from Demographic
Danny Leipziger +3 more
core
Process Evaluation of Georgia's Integrated Family Support Demonstration Project: Findings from First Year Implementation Efforts [PDF]
This report summarizes findings from first year implementation efforts of the Georgia Department of Human Resources' Family Support Demonstration Project. The goal of the project was to reduce child abuse and neglect and improve child health by providing
Amanda Phillips Martinez +4 more
core
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Early Childbirth, Health Inputs and Child Mortality: Recent Evidence from Bangladesh [PDF]
This paper examines the relationship between early childbearing, parental use of health inputs and child mortality in Bangladesh. In order to account for the potential endogeneity of the age at birth and use of health inputs, (hospital delivery and child
Pushkar Maitra, Sarmistha Pal
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Mohamed Abdi Hassan,1 Dorayis Castillo Lopez,1 Melvis Bernis Maren Snr,1 Walyeldin Elnour Mohamed Elfakey,1,2 Kadijo Mohamed Bule,1 Abdullahi Hussein Ahmed,1 Mohamed Jayte,1 Libaan Hassan Mohamud,1 Mohamed Mohamud Farah,1 Abdikadir Adan Abdullahi,1 Ezera
Hassan MA +10 more
doaj
The Dynamics of Income-related Health Inequality among US Children [PDF]
We estimate and decompose family income-related inequality in child health in the US and analyze its dynamics using the income-related health mobility index recently introduced byAllanson et al., 2010. Data come from the 1997, 2002, and 2007 waves of the
Jingya Song +2 more
core
Child Care Feeding Programs Support Young Children's Healthy Development [PDF]
New research by Children's HealthWatch shows that toddlers from low-income families who receive meals from their child care provider - those likely to be receiving CACFP - are in better health, have decreased risk for hospitalization, and are at ...
Annie Gayman +5 more
core

