Results 91 to 100 of about 1,286,243 (296)

The Role of the Certified Strength and Conditioning Specialist in Preventing Childhood Obesity

, 2006
Obesity is a leading cause of many chronic diseases. The likelihood of adult obesity increases if one is obese as a child. Certified Strength and Conditioning Specialist professionals in the high school setting can promote health and fitness to our youth
Brumitt, Jason
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Birth order and reproductive stoppage in families of children with autism spectrum disorder

Psychiatry and Clinical Psychopharmacology, 2019
OBJECTIVES: The objective of the study was to evaluate the birth order of children with Autism Spectrum Disorder (ASD) and ways of delivery at birth, together with the phenomenon of reproductive stoppage and the number of siblings in the case families ...
Cagatay Ugur, Aysegul Tonyali, Zeynep Goker, Ozden Sukran Uneri   +3 more
doaj   +1 more source

The Impact of Childhood Health on Adult Educational Attainment: Evidence from Modern Mandatory School Vaccination Laws [PDF]

This paper examines the impact of post-neonatal childhood health on adult educational attainment using evidence from mandatory school vaccination laws in the U.S.
Dara N. Lee
core  

The health of women and girls determines the health and well-being of our modern world: A White Paper From the International Council on Women's Health Issues [PDF]

, 2011
The International Council on Women's Health Issues (ICOWHI) is an international nonprofit association dedicated to the goal of promoting health, health care, and well-being of women and girls throughout the world through participation, empowerment ...
Afaf I. Meleis, Alban A., Anne Teitelman, Asaria P., Beaglehole R., Breman J. G., Carolyn Sampselle, Chenoweth D., Correa-de-Araujo R., DeAnne K. H. Messias, Debra Anderson, Doris Schaeffer, Eleanor Krassen Covan, Hazel Brown, Jacquelyn C. Campbell, Josefina A. Tuazon, Karen Reesman, Kettel B., Laurance W., Mane P., Margarethe Hochleitner, Marilyn S. Sommers, Marilyn Stringer, Marmot M., Michelle DiGiacomo, Patricia M. Davidson, Phillips J., Phyllis Stern, Reddy K. S., Richmond R., Rosaly Correa-de-Araujo, Rosenfield A., Sachs J. D., Sankaran G., Sarah J. McGrath, Shaw D., Siriorn Sindhu, Solina Richter, Tessa Dharmendra, Wilson G., Yingjuan Cao   +40 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Impact of MEFV mutations on inflammatory activity and long-term relapse in pediatric IgA vasculitis

BMC Pediatrics
Background IgA vasculitis (IgAV) is the most common childhood small-vessel vasculitis. MEFV variants may enhance innate inflammatory responses, but their effect on disease course remains unclear.
Göktuğ Özdemir, Esma Kaya Özdemir, Asım Gültekin   +2 more
doaj   +1 more source

Subclinical Myocardial Dysfunction Demonstrated by Speckle Tracking Echocardiography in Children with Euthyroid Hashimoto’s Thyroiditis

JCRPE, 2019
Objective:Thyroid hormones have an important role in the regulation of the cardiovascular system. The aim of this study was to investigate the presence of subclinical myocardial dysfunction in children with euthyroid Hashimoto’s thyroiditis (eHT) without
Emine Azak, Seyit Ahmet Uçaktürk, İbrahim İlker Çetin, Hazım Alper Gürsu, Eda Mengen, Utku Pamuk   +5 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Vitamin D replacement therapy may regulate sleep habits in patients with restless leg syndrome

Open Medicine
The aim of this study is to determine the effect of vitamin D replacement therapy on sleep habits in restless legs syndrome (RLS) patients with vitamin D deficiency.
Kahraman Feyza Ustabaş, Demir Ayşegül Doğan, Yazıcı Mebrure, Çakır Fatma Betül, Temel Hayrettin, Çollak Abdülhamit, Erenberk Ufuk   +6 more
doaj   +1 more source