Results 111 to 120 of about 1,286,243 (296)

Acute Poisoning in Pediatric Emergency Department: A 5-Year Analysis

open access: yesCerrahpaşa Medical Journal
Objective: This study aimed to delineate the etiology, clinical, and demographic characteristics of pediatric patients presenting to the emergency service with poisoning complaints and to evaluate the treatment processes retrospectively.
Ömer Osman Dağ   +2 more
doaj   +1 more source

Global estimates and projections of mortality by cause, 1970-2015 [PDF]

open access: yes
The authors report estimates and projections of deaths by cause for major world regions, based on data from country reports to the World Health Organization and regression models.
Bulatao, Rodolfo A.   +1 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Evaluation of consultations of children and adolescents with type 1 diabetes

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: In this study, we aimed to evaluate socio-demographic properties, diagnoses and drug use of children and adolescents with type 1 diabetes.
Senay Celenay   +3 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Turkish Validity and Reliability of Pediatric Sleep Practices Questionnaire

open access: yesArchives of Health Science and Research, 2023
Arzu SARIALIOĞLU   +2 more
doaj   +1 more source

Child mortality in South Asia: preventable diseases and scaling up immunisation efforts [PDF]

open access: yes, 2016
To accelerate robust growth and aspire to global power status, South Asian countries must improve their child health indicators. Drawing on her professional advocacy and communications experience in South Asia, Krupa Shah discusses the availability of ...
Shah, Krupa
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy