Results 101 to 110 of about 640,820 (294)

Advanced Techniques for Modelling Maternal and Child Health in Africa

open access: yes, 2013
More than ten million women die or experience adverse consequences during pregnancy and childbirth each year (WHO 2005). Furthermore, nearly nine million children under the ages of 5 years die each year, largely from preventable and treatable diseases ...
Gebrenegus Ghilagaber   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Vitamin D replacement therapy may regulate sleep habits in patients with restless leg syndrome

open access: yesOpen Medicine
The aim of this study is to determine the effect of vitamin D replacement therapy on sleep habits in restless legs syndrome (RLS) patients with vitamin D deficiency.
Kahraman Feyza Ustabaş   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Subclinical Myocardial Dysfunction Demonstrated by Speckle Tracking Echocardiography in Children with Euthyroid Hashimoto’s Thyroiditis

open access: yesJCRPE, 2019
Objective:Thyroid hormones have an important role in the regulation of the cardiovascular system. The aim of this study was to investigate the presence of subclinical myocardial dysfunction in children with euthyroid Hashimoto’s thyroiditis (eHT) without
Emine Azak   +5 more
doaj   +1 more source

Contextual Effect of the Integrated Health Post and Social Capital on Completeness of Child Immunization in Pacitan, East Java

open access: yes, 2020
Background: Around 2-3 million deaths each yearwere caused by diseases that could be pre­vented by immunization. Immunization is an effort to actively increase a person's immunity against a disease.
Rahardjo, Setyo Sri   +2 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Birth order and reproductive stoppage in families of children with autism spectrum disorder

open access: yesPsychiatry and Clinical Psychopharmacology, 2019
OBJECTIVES: The objective of the study was to evaluate the birth order of children with Autism Spectrum Disorder (ASD) and ways of delivery at birth, together with the phenomenon of reproductive stoppage and the number of siblings in the case families ...
Cagatay Ugur   +3 more
doaj   +1 more source

Integrating services for maternal, newborn and child health and noncommunicable diseases at district- level facilities: Viet Nam country perspective

open access: yes
vii, 71 p.This country perspective analyses the burden of noncommunicable diseases (NCDs) among women in Viet Nam, including during pregnancy and the postnatal period, and examines opportunities to integrate NCD prevention and control into maternal ...
World Health Organization
core  

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