Results 71 to 80 of about 1,477,434 (241)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Generation Z's Preferences for Messages of Happiness

open access: yesKomunika
The rise of digital da'wah has shifted religious learning for Generation Z to online platforms, but a clear understanding of their content preferences remains a research gap.
Farikhatul 'Ubudiyah, Primi Rohimi
doaj   +1 more source

A Story of their own: Adolescent Pregnancy and Child Welfare in Aboriginal Communities

open access: yes, 2007
The phenomenon of adolescent pregnancy and its relationship to child welfare in Aboriginal communities provides a useful lens through which to understand fundamental and structural problems with the current child welfare system in Canada.
Ordolis, Emilia
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Exploring the digital influence of Generation Alpha on purchase behaviors of working mothers

open access: yesDiscover Psychology
In the digital age, Generation Alpha social media influencers (children aged 1–15 years) are emerging as powerful agents shaping consumer behavior.
Syeda Aneeqa Touseef   +4 more
doaj   +1 more source

Talking about the Aboriginal Community: Child Protection Practitioners’ Views

open access: yes, 2004
Child protection practitioners view Aboriginal communities as victim, adversary, participant, partner, and protector of children. These representations ofcommunities are derived from interview data with 19 Aboriginal and nonAboriginal child protection ...
Walmsley, Christopher
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Contribution à l’étude des facteurs de déconstruction et de reconstruction de la personnalité et la qualité d’attachement chez les enfants placés sous recueil légal

open access: yesRevue des Sciences Humaines, 2015
Cette recherche est une étude clinique visant à identifier les différents facteurs pouvant influencer la construction de la personnalité, ainsi que la qualité d’attachement chez les enfants Algériens nés sous X, recueillis légalement dans des familles ...
Rania BOUBEKIRIA, Mohamed Nadjib NINI
doaj  

Children’s privacy, autonomy, and digital identity in sharenting research: a scoping review with bibliometric mapping

open access: yesFrontiers in Psychology
IntroductionResearch on digital parenting and sharenting has expanded rapidly, yet the literature remains distributed across media studies, child development, communication, law, and health-related domains.
Osman Akay
doaj   +1 more source

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