Results 91 to 100 of about 1,477,434 (241)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

“Why would we?” A qualitative study on COVID-19 vaccination decision making among Ukrainian economic female migrants in Poland

Frontiers in Public Health
BackgroundUkraine has one of the lowest COVID-19 vaccination rates in Europe. This may pose a significant epidemiological risk in the context of the refugee crisis and the fact that, since 2020, SARS-CoV-2 has been spreading and changing globally ...
Maria Ganczak, Pawel Kalinowski, Piotr Twardowski, Dominika A. Osicka, Oskar Pasek, Łukasz Duda-Duma, Johanna P. M. Vervoort, Michael Edelstein, Marta Kowalska   +8 more
doaj   +1 more source

Understanding child neglect [PDF]

, 2014
Child neglect is one of the most common forms of maltreatment. Neglect is a topic that encompasses complex issues, many of which are also emerging research areas. This paper aims to provide a broad overview of these issues in relation to current thinking
Debbie Scott
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Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Influence from the intestinal microbiota of neonate on early child development

BMC Pediatrics
Objective The early-life microbiome is gaining appreciation as a major influencer in human development and long-term health. The present study explored the influence from the intestinal microbiota of neonate on early child development.
Yuan Zhang, Wei Zheng, Xin Yan, Ya Zhang, Bo Peng, Di Wu, Lirui Zhang, Huiyuan Pang, Ruihua Yang, Yuanyuan Wang, Guanghui Li, Xu Ma   +11 more
doaj   +1 more source

Consumers' judgement on influencer marketing

, 2019
Szakdolgozatomat napjaink egyik meghatározó témájáról az influencer marketingről és annak a lakossági megítéléséről írtam. Mivel manapság az internet életünk fontos részévé vált, és az influencer marketing robbanásszerűen terjed az egész világon, ezzel ...
Gergely, Noémi
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MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

From counsel to consumption: examining sociocultural influences on perinatal nutrition in rural India

Frontiers in Nutrition
Perinatal nutrition is vital for better maternal and child health outcomes. Biomedical guidelines recommend increasing caloric intake, avoiding toxins, and consuming a diverse, nutritious diet during pregnancy and postpartum.
Faiz A. Hashmi, Cristine H. Legare
doaj   +1 more source

Child Support Services Handbook

, 2013
application/pdfThe Kansas Child Support Services (CSS) program helps children receive the financial support necessary for their growth and development.
Kansas Child Support Services.
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