Results 11 to 20 of about 578 (190)

How the placenta-brain lipid axis impacts the nutritional origin of child neurodevelopmental disorders: Focus on attention deficit hyperactivity disorder and autism spectrum disorder

Experimental Neurology, 2022
Dietary fish is a rich source of omega-3 (n-3) fatty acids, and as such, is believed to have played an important role in the evolution of the human brain and its advanced cognitive function. The long chain polyunsaturated fatty acids, particularly the n-3 docosahexanoic acid (DHA), are critical for proper neurological development and function. Both low
Tarui, Tomo, Rasool, Aisha, O’Tierney-Ginn, Perrie   +2 more
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Critical Role of TLR4 on the Microglia Activation Induced by Maternal LPS Exposure Leading to ASD-Like Behavior of Offspring

Frontiers in Cell and Developmental Biology, 2021
Objective: To investigate the role of TLR4 on the microglia activation in the pre-frontal cortex, which leads to autism-like behavior of the offspring induced by maternal lipopolysaccharide (LPS) exposure.Methods: Pregnant TLR4−/− (knockout, KO) and WT ...
Lu Xiao, Lu Xiao, Junyan Yan, Junyan Yan, Di Feng, Di Feng, Shasha Ye, Shasha Ye, Ting Yang, Ting Yang, Hua Wei, Hua Wei, Tingyu Li, Tingyu Li, Wuqing Sun, Jie Chen, Jie Chen   +16 more
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China Multi-Center Preschool Autism Project (CMPAP): Design and Methodologies to Identify Clinical Symptom Features and Biomarkers of Autism Spectrum Disorders

Frontiers in Psychiatry, 2021
Background: The etiology of autism spectrum disorder (ASD) has not yet been fully identified, but it seems to be triggered by complex genetic and environmental risk factors.
Ting Yang, Jiang Zhu, Qiu Li, Li Chen, Li-Jie Wu, Fei-Yong Jia, Yan Hao, Xiao-Yan Ke, Ming-Ji Yi, Chun-Hua Jin, Jie Chen, Ting Yu Li   +11 more
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Valproic Acid Induces Autism-Like Synaptic and Behavioral Deficits by Disrupting Histone Acetylation of Prefrontal Cortex ALDH1A1 in Rats

Frontiers in Neuroscience, 2021
ObjectivesThis study aimed to investigate the impact of valproic acid (VPA) on the histone acetylation of acetaldehyde dehydrogenase 1A1 (ALDH1A1) and the mechanism underlying VPA-induced autism-like behavior.MethodsFemale Sprague-Dawley rats were ...
Huan Liu, Huan Liu, Mei Tan, Mei Tan, Boli Cheng, Boli Cheng, Si Wang, Si Wang, Lu Xiao, Lu Xiao, Jiang Zhu, Jiang Zhu, Qionghui Wu, Qionghui Wu, Xi Lai, Xi Lai, Qian Zhang, Qian Zhang, Jie Chen, Jie Chen, Tingyu Li, Tingyu Li   +21 more
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The Gut Microbiota and Associated Metabolites Are Altered in Sleep Disorder of Children With Autism Spectrum Disorders

Frontiers in Psychiatry, 2020
BackgroundAutism spectrum disorder (ASD) is a type of neurodevelopmental disease that is frequently accompanied by sleep disorder. Herein, we investigated changes in the gut microbiota and its metabolites correlated with core symptoms and sleep problems ...
Xueying Hua, Xueying Hua, Jiang Zhu, Jiang Zhu, Ting Yang, Ting Yang, Min Guo, Min Guo, Qiu Li, Qiu Li, Jie Chen, Jie Chen, Tingyu Li, Tingyu Li   +13 more
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Characteristics and Risk Factors of Children Requiring Prolonged Mechanical Ventilation vs. Non-prolonged Mechanical Ventilation in the PICU: A Prospective Single-Center Study

Frontiers in Pediatrics, 2022
BackgroundProlonged mechanical ventilation (PMV) has become an enormous challenge in intensive care units (ICUs) around the world. Patients treated with PMV are generally in poor health. These patients represent a select cohort with significant morbidity,
Yanling Liu, Yanling Liu, Yanling Liu, Qingyue Wang, Qingyue Wang, Qingyue Wang, Jun Hu, Jun Hu, Jun Hu, Fang Zhou, Fang Zhou, Fang Zhou, Chengjun Liu, Chengjun Liu, Chengjun Liu, Jing Li, Jing Li, Jing Li, Yueqiang Fu, Yueqiang Fu, Yueqiang Fu, Hongxing Dang, Hongxing Dang, Hongxing Dang   +23 more
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A structural equation model of the relationship among occupational stress, coping styles, and mental health of pediatric nurses in China: a cross-sectional study

BMC Psychiatry, 2022
Background Pediatric nurses experience a wide rang of stressful events at work every day, which can trigger a lot of emotional responses. The objectives of this study were mainly to explore the potential interrelationships of occupational stress, coping ...
Yating Zhou, Xiaoli Guo, Huaying Yin
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Effects of psychosocial function in pediatric-onset inflammatory bowel disease during the coronavirus disease 2019 pandemic

Frontiers in Pediatrics, 2023
Background and AimsResearch on the effect of the coronavirus disease 2019 (COVID-19) pandemic on psychosocial function in patients with pediatric-onset inflammatory bowel disease (PIBD) is limited. This study aimed to evaluate the psychological status of
Huihui Zhang, Yun Yang, Xixi Zhao, Huajian Hu, Jia Liu, Xue Zhan, Xiaomei Song, Hong Guo, Zhongyue Li, Xiaoqin Zhou   +9 more
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Exploring the association between child nutritional disorders and short birth interval: Evidence from 2017/18 Bangladesh Demographic and Health Survey data

Clinical Epidemiology and Global Health, 2023
Background: Nutritional disorder is an ongoing public health threat in Low- and Middle-Income Countries (LMICs) which is assumed to be higher among children born in shorter intervals (Short Birth Interval, SBI). However, high-quality research addressing this is lacking. We explored the association of nutritional disorder with SBI adjusting for possible
Mohammad Zahidul Islam, Mostafizur Rahman, Nuruzzaman Khan   +2 more
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Protective Effects of Appropriate Amount of Nuts Intake on Childhood Blood Pressure Level: A Cross-Sectional Study

Frontiers in Medicine, 2022
ObjectiveIncreased blood pressure (BP) is a major risk factor for cardiovascular disease (CVD) in adults. Regular consumption of nuts may improve some BP in adults whereas evidence in children is relatively lacking.
Ye Feng, Ye Feng, Yang Bi, Xian Tang, Ping Zhang, Jishuang Tong, Xin Peng, Jie Tian, Xiaohua Liang   +8 more
doaj   +1 more source