Results 81 to 90 of about 248,682 (284)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Autoinducer-2 promotes the colonization of Lactobacillus rhamnosus GG to improve the intestinal barrier function in a neonatal mouse model of antibiotic-induced intestinal dysbiosis

Journal of Translational Medicine
Background Human health is seriously threatened by antibiotic-induced intestinal disorders. Herein, we aimed to determine the effects of Autoinducer-2 (AI-2) combined with Lactobacillus rhamnosus GG (LGG) on the intestinal barrier function of antibiotic ...
Riqiang Hu, Ting Yang, Qing Ai, Yuan Shi, Yanchun Ji, Qian Sun, Bei Tong, Jie Chen, Zhengli Wang   +8 more
doaj   +1 more source

Examining the influence of child nutritional disorders on early childhood development in Bangladesh: insights from the multiple indicator cluster survey

Public Health Nutrition
Abstract Objective: The objective of this study was to explore the relationship between various forms of child nutritional disorders and early childhood development in Bangladesh. Design: We analysed data from the nationally representative cross-sectional 2019 Multiple Indicator Cluster Survey.
Shimlin Jahan Khanam, Md Nuruzzaman Khan
openaire   +4 more sources

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

A Study on the Peak‐to‐Valley Characteristics of Intellectual Structure in Low‐Functioning Children With Autism Spectrum Disorder

Pediatric Discovery
Autism Spectrum Disorder (ASD) is marked by a distinctive cognitive profile reflecting neurodiversity, yet whether this profile extends consistently across the functional spectrum remains uncertain.
Danyang Zhang, Qiuhong Wei, Binyue Hu, Dan Ai, Yu Zhang, Xueli Xiang, Ting Yang, Qian Zhang, Qian Chen, Min Guo, Jie Chen, Tingyu Li, Hua Wei   +12 more
doaj   +1 more source

Effects of S24–7 on the weight of progeny rats after exposure to ceftriaxone sodium during pregnancy

BMC Microbiology, 2021
Antibiotic exposure during pregnancy will adversely affect the growth of offspring; however, this remains controversial and the mechanism is poorly understood.
Xin Yang, Ting Tang, Jing Wen, Mengchun Li, Jie Chen, Tingyu Li, Ying Dai, Qian Cheng   +7 more
doaj   +1 more source

Iodine status during pregnancy in India and related neonatal and infant outcomes [PDF]

, 2013
Objective: To document iodine status in Indian pregnancies, associations with maternal diet and demographics, and offspring developmental measures.
Andersson, Blazer, Bleichrodt, Chakraborty, Chakraborty, Chanoine, Chittaranjan S Yajnik, Dattatray S Bhat, Deepa A Raut, Emilie Combet, Hamrosi, Himangi G Lubree, Kapil, Kapil, Kapil, Kapil, Katre, Kochupillai, Kumar, Mackerras, Mazumdar, Mike EJ Lean, Misra, Morven IFA Lean, Rao, Rendina, Saikia, Sooch, Suyog M Joshi   +28 more
core   +2 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source