Results 91 to 100 of about 1,334,692 (318)

Mothers' perspectives on learning through play in the home

, 2016
Research in the field of early childhood education and care (ECEC) indicates that if educators can align their perspectives and practices with families' perspectives, children's educational outcomes will improve.
Colliver, Yeshe
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Latent profiles of parents’ family-of-origin invalidation experiences: associations with emotion coping and children’s prosocial behavior

Humanities & Social Sciences Communications
The development of prosocial behavior, a vital aspect of children’s socialization and future mental health, remains understudied in its relationship to parents’ family-of-origin experiences. The goal of the present study is to examine how parents’ family-
Youli Wang, Honghuan Fang, Baocheng Pan, Jingkai Sun, Ziyi Feng, Bijing Ren, Keman Yuan, Pin Xu, Bowen Xiao, Yan Li   +9 more
doaj   +1 more source

Early childhood teachers and regulation : complicating power relations using a Foucauldian lens

, 2006
Paper presented at the Reconceptualizing Early Childhood Education (RECE), Research, Theory and Practice Conference, Rotorua.1 page ...
Fenech, Marianne, Sumsion, Jennifer
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Thyroid function test evolution in children with Hashimoto’s thyroiditis is closely conditioned by the biochemical picture at diagnosis

Italian Journal of Pediatrics, 2018
ᅟ Aim of this commentary is to summarize the salient literature views on the relationships between presentation and evolution patterns of thyroid function in children with Hashimoto’s thyroiditis (HT).
Giuseppe Crisafulli, Romina Gallizzi, Tommaso Aversa, Giuseppina Salzano, Mariella Valenzise, Malgorzata Wasniewska, Filippo De Luca, Giuseppina Zirilli   +7 more
doaj   +1 more source

Early childhood portfolios as a tool for enhancing learning during the transition to school

, 2009
From 2005-2008 Mangere Bridge Kindergarten in New Zealand carried out a Centre of Innovation research project exploring the transition between early childhood education and school.
Peters, Sally, Carr, Margaret, Rogers, Pat, Smith, Jemma, Hartley, Carol   +4 more
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Co-parenting, parental competence and problem behaviours in children: examining differential parental roles

Humanities & Social Sciences Communications
In recent years, the increase in child problem behaviours has become a significant public health concern. It is crucial to understand the complex dynamics between parental co-parenting, parenting competence, and child problem behaviours to develop ...
Baocheng Pan, Youli Wang, Chengli Zhao, Jiaxuan Miao, Yizhao Gong, Bowen Xiao, Yan Li   +6 more
doaj   +1 more source

Early Childhood Education as Sites for Children’s Citizenship: Tensions, challenges and possibilities in New Zealand’s policy framing

, 2010
This paper draws on recent research to examine the tensions and challenges inherent in the current market approach to provision of Early Childhood Care and Education (ECCE) services in Aotearoa New Zealand.
Mitchell, Linda, Davison, Claire
core