Results 101 to 110 of about 1,607,316 (314)

Fish oil and vitamin D in pregnancy for the prevention of early childhood asthma: study protocol for two double-blinded, randomised controlled trials

BMJ Open
Introduction Previous randomised controlled trials (RCTs) have indicated a protective role of pregnancy supplementation with fish oil and high-dose vitamin D, respectively, on offspring asthma, infections and several other disorders in early childhood ...
Klaus Bønnelykke, Jakob Stokholm, Rebecca Vinding, Bo Chawes, Julie Nyholm Kyvsgaard, Ulrik Ralfkiaer, Marianne Mikkelsen, Nicklas Brustad, Sarah Brandt, Nilo Vahman   +9 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Trajectories of resting energy expenditure and performance of predictive equations in children hospitalized with an acute illness and malnutrition: a longitudinal study

Scientific Reports
There is scarce data on energy expenditure in ill children with different degrees of malnutrition. This study aimed to determine resting energy expenditure (REE) trajectories in hospitalized malnourished children during and after hospitalization.
Farzana Afroze, Farnaz Khoshnevisan, Philliness Prisca Harawa, Zahidul Islam, Celine Bourdon, Stanley Khoswe, Munirul Islam, Shafiqul Alam Sarker, Farhana Islam, Abu Sadat Mohammad Sayeem Bin Shahid, Koen Joosten, Jessie M. Hulst, Chisomo Eneya, Judd L. Walson, James A. Berkley, Isabel Potani, Wieger Voskuijl, Tahmeed Ahmed, Mohammod Jobayer Chisti, Robert H. J. Bandsma   +19 more
doaj   +1 more source

Multiple Ways of Knowing and Seeing: Reflections on the Renewed Vigour in Early Childhood Research [PDF]

, 2004
This paper reflects on the current state of research in early childhood education and proposes that there is a renewed interest in research evident at present.
Nolan, Andrea, Kilderry, Anna, Noble, Karen   +2 more
core  

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Tetramethylpyrazine potentiates arsenic trioxide activity against HL-60 cell lines

Brazilian Journal of Medical and Biological Research, 2012
The objective of this study was to evaluate the effects of tetramethylpyrazine (TMP) in combination with arsenic trioxide (As2O3) on the proliferation and differentiation of HL-60 cells.
Yuni Wu, Youhua Xu, Yali Shen, Cuicui Wang, Gaili Guo, Tiantian Hu   +5 more
doaj  

HOW ARE YOU FEELING TODAY? – Gaps and opportunities in capturing patient reported outcomes (PROs) in Pediatric Cancer Care

EJC Paediatric Oncology
Including children's perspectives in healthcare and clinical trials, particularly in pediatric oncology, is critical to promoting child-centered care. Research has shown that even very young children can understand complex medical concepts, highlighting ...
Anna Zettl, Hannah Gsell, Karolina Maślak, Antti Karjalainen, Ulrike Leiss, Anita Kienesberger, Carina Schneider   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Early childhood services: What can children tell us? [PDF]

, 2002
This paper presents child data generated in a pilot project of the ACCESS Study of Child and Family Services, a research program of how child and family services align with the interests and needs of local families. Underpinned by social capital theories,
Tennent, Lee, Farrell, Ann, Tayler, Collette P.   +2 more
core  

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source