Results 101 to 110 of about 1,334,692 (318)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Perspectives of fathers on the importance of learning through play among pre-primary-aged children in Nigeria

International Journal of Child Care and Education Policy
Play is integral to early childhood development, fostering skills crucial for holistic growth. While the role of mothers supporting children’s play has been widely studied, there is limited research on fathers’ roles, despite evidence suggesting a ...
Tolulope Ojo, Samuel Salama, Yetunde Oluwatosin, Patricia Falope   +3 more
doaj   +1 more source

Quality of Early Childhood Education and Care in Kazakhstan: The First Nationwide Study

Вопросы образования
Currently, Kazakhstan has the highest enrolment rate in the history of early childhood education and care (ECEC), with 98% enrolment for children aged three to six years old. With this significant expansion of ECEC, there is a lack of sufficient evidence
Gaukhar Kiikova, Altynay Bektemirova, Aizhan Ramazanova, Zhazira Issina, Sogdiana Chukurova   +4 more
doaj   +1 more source

The communication accretion spiral : a communication process for promoting and sustaining meaningful partnerships between families and early childhood service staff

, 2005
Findings of an investigation of parents' perceptions of early childhood service quality identified limitations in staff-parent communication which inhibit the development of a shared parent and staff approach to children's care and education.
Elliott, Roslyn
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Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

From family to school: the dual protection of father-child relationship and teacher-student relationship on children’s mental health problems

BMC Psychology
Mental health problems among children are a significant public health concern. Family dynamics and early educational environments are critical in shaping children’s mental health.
Youli Wang, Baocheng Pan, Honghuan Fang, Jingkai Sun, Bijing Ren, Ziyi Feng, Bowen Xiao, Pin Xu, Yan Li   +8 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Empowering Early Childhood Education Teachers through digital early literacy assessment program

Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang
This community service program addressed the limited capacity of early childhood education (PAUD) teachers to conduct systematic and contextual initial literacy assessments.
Martha Christianti, Nur Hayati, Nur Cholimah, Ika Budi Maryatun, Rosida Nur Kasanah, Yovinka Agista Putri, Firqotul Arifah, Bima Putro Wijayanto, Sazliana Idmi Martuaji, F Devi Kurnia   +9 more
doaj   +1 more source

Childhood diabetes database. Chinese

, 2007
Translation of: Childhood diabetes database.Title from PDF caption (viewed on May 12, 2009)."Chinese DHS 8581 (Rev.5/2007)."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

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