Results 141 to 150 of about 31,323 (242)

Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms. [PDF]

Brain, 2020
Miao QL, Herlitze S, Mark MD, Noebels JL.   +3 more
europepmc   +1 more source

The burden of the postictal state in epilepsy: A prospective, single‐center observational cohort study

Epileptic Disorders, EarlyView.
Abstract Objective The postictal state is a major yet underrecognized component of the epilepsy burden. We aimed to develop a structured patient‐reported instrument to quantify postictal recovery, characterize its multidimensional burden, and identify demographic, clinical, psychiatric, and treatment‐related factors associated with postictal severity ...
Ionuț‐Flavius Bratu, Agnès Trébuchon, Fabrice Bartolomei   +2 more
wiley   +1 more source

Occipital irregular delta activity in focal epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective Nonspecific occipital irregular delta activity (OID) is a common finding in focal epilepsy (FE). However, the significance of OID and its relationship to the underlying etiology of FE remain largely unstudied. This study aimed to investigate the relationship between OID and the etiology of FE, as well as the relationship between OID ...
Mónika Bessenyei, Miklós Emri, Johanna Dömötör, Béla Clemens   +3 more
wiley   +1 more source

Unique EEG signature of atypical absence seizures in SYNGAP1‐related developmental and epileptic encephalopathy

Epileptic Disorders, EarlyView.
Rainier Mark Loidor L. Rapal, Joshua Chang, Douglas Nordli III   +2 more
wiley   +1 more source

The effectiveness of adding on or switching antiseizure medications after the first fails to control focal epilepsy: A systematic review of randomized controlled trials

Epileptic Disorders, EarlyView.
Abstract Focal epilepsy constitutes 60–70% of epilepsy, and up to half of patients do not achieve seizure freedom with their first antiseizure medication (ASM). When the first ASM fails, evidence guiding whether to switch or add‐on another ASM and which ASMs to use is limited. This review synthesized evidence from randomized controlled trials (RCTs) on
Isaac J. Egesa, Gashirai Mbizvo, Michelle Maden, Thomas Spain, Richard Emsley, Laura J. Bonnett, Anthony G. Marson, Catrin Tudur Smith   +7 more
wiley   +1 more source

Metabolic mimicry of perioral myoclonia with absences: A signature of thalamocortical instability in childhood‐onset ornithine transcarbamylase deficiency

Epileptic Disorders, EarlyView.
José Augusto Bragatti, Letícia Grigoletto   +1 more
wiley   +1 more source

Electroclinical phenotypes—genetic characterization of developmental and epileptic encephalopathies in a cohort study

Epileptic Disorders, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman, Fulya Kurekci, Sinan Akbas, Ceyda Oney, Mehmet Akif Kilic, Hulya Maras Genc, Ayca Dilruba Aslanger, Edibe Pembegul Yildiz   +7 more
wiley   +1 more source

Clinical Vignette: Piperacillin/tazobactam‐associated myoclonic status epilepticus in a patient with end‐stage renal failure on hemodialysis

Epileptic Disorders, EarlyView.
O. M. Malanga, G. Giovannelli, G. Pastorelli, S. Fittante, A. Poggesi, E. Rosati   +5 more
wiley   +1 more source

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

Epileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini, Evripidis Pityrigkas, Zoi Kallia, Georgia Pepe, Antonis Frontistis, Dimitrios Profer, Vasilios Kimiskidis   +6 more
wiley   +1 more source

Aphasic status epilepticus due to Epstein–Barr virus meningoencephalitis – A clinical vignette

Epileptic Disorders, EarlyView.
Gemma Bassani, Tobias Moser, Lukas Machegger, Fabio Rossini, Georg Pilz, Eugen Trinka, Giorgi Kuchukhidze   +6 more
wiley   +1 more source