Results 101 to 110 of about 414,419 (312)

Tumor-Associated Macrophages in Oncolytic Virotherapy: Friend or Foe?

Biomedicines, 2016
Cancer therapy remains a challenge due to toxicity limitations of chemotherapy and radiation therapy. Oncolytic viruses that selectively replicate and destroy cancer cells are of increasing interest.
Nicholas L. Denton, Chun-Yu Chen, Thomas R. Scott, Timothy P. Cripe   +3 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Prenatal factors, childhood growth trajectories and age at menarche. [PDF]

, 2002
BACKGROUND: In recent studies a larger birth size has been shown to delay the timing of menarche. The mechanisms underlying this association are not clear, however, as birthweight is a predictor of body size in childhood, and a large body size is known ...
De Stavola, Bianca L, Mann, Vera, Wadsworth, Michael EJ, dos Santos Silva, Isabel, Hardy, Rebecca, Kuh, Diana   +5 more
core   +1 more source

Assessing Contributory Factors of Diarrhea Among Under‐Five Children in Bangladesh From 2006 to 2019 and Recent Increases: A Cross‐Sectional Study

Health Science Reports
Background and Aims One‐third of all child deaths in this country are caused by diarrhea. The burden of the disease appears to be increasing in recent years in Bangladesh.
Mohammad Nayeem Hasan, M. Noor‐e‐alam Siddiqui, Mst. Farzana Akter, Sabikunnaher Mitu, Muhammad Abdul Baker Chowdhury, Md Jamal Uddin   +5 more
doaj   +1 more source

Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity

Molecular Therapy: Oncolytics, 2014
Multiple studies have indicated that in addition to direct oncolysis, virotherapy promotes an antitumor cytotoxic T cell response important for efficacy.
Jennifer L Leddon, Chun-Yu Chen, Mark A Currier, Pin-Yi Wang, Francesca A Jung, Nicholas L Denton, Kevin M Cripe, Kellie B Haworth, Michael A Arnold, Amy C Gross, Timothy D Eubank, William F Goins, Joseph C Glorioso, Justus B Cohen, Paola Grandi, David A Hildeman, Timothy P Cripe   +16 more
doaj   +1 more source

Public awareness for "classic" childhood diseases and inflammatory syndromes in children during the COVID-19 pandemic. [PDF]

J Pediatr Nurs, 2022
Zieger M, Strzelecki A, Springer S.
europepmc   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Epidemiological situation of measles in the Republic of Kazakhstan

International Journal of Infectious Diseases, 2020
A. Zhuzzhasarova, D. Bayesheva, B. Turdalina, A. Aimahanbetovna   +3 more
doaj   +1 more source

The endocrinological aspects of Down's syndrome

Сеченовский вестник, 2014
The article considers the role of the endocrinologist in the treatment of patients with Down syndrome. Particular attention is paid to the diagnosis and therapy, an integrated approach to the treatment of complex patients taking into account features of ...
A. V. Vitebskaya
doaj  

Validation of Childhood Rare Epilepsy Social Impact Assessment (CRESIA) to Measure the Social and Family Impact of Rare Childhood Diseases with Epilepsy. [PDF]

J Clin Med, 2022
Salom R, Aras LM, Piñero J, Duñabeitia JA.   +3 more
europepmc   +1 more source