Results 81 to 90 of about 414,419 (312)

Genetic control of active neural circuits

Frontiers in Molecular Neuroscience, 2009
The use of molecular tools to study the neurobiology of complex behaviors has been hampered by an inability to target the desired changes to relevant groups of neurons.
Leon Reijmers, Leon Reijmers, Mark Mayford, Mark Mayford   +3 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Experiences of registered nurses of their role in carrying out the induced sputum procedure in diagnosing childhood Tuberculosis [PDF]

, 2011
Tuberculosis (TB) is an ancient disease dating back at least 5000 years, but the TB epidemic is said to be getting worse than at any other time in history (Puri & John, 1997: 12).
Isaacs, Whasiefa
core  

Cause-specific hospital admission and mortality among working men: association with socioeconomic circumstances in childhood and adult life, and the mediating role of daily stress [PDF]

, 2005
BACKGROUND: The aim of this study was to investigate the association of childhood and adulthood social class with the occurrence of specific diseases, including those not associated with a high mortality rate, and to investigate daily stress as the ...
Sterne, JAC, Macleod, J, Hart, CL, Macleod, John, Heslop, P., Metcalfe, C, MacLeod, J., Heslop, P, Davey Smith, G., Hart, C.L., Davey Smith, G, Metcalfe, C., Sterne, J.A.C.   +12 more
core   +1 more source

Analysis of evolution of the policy framework and governance mechanisms and their influence on the institutionalisation process of integrated community case management in Burkina Faso between 2010 and 2024: a scoping review

Frontiers in Public Health
ContextIntegrated Community Case Management (iCCM) has been implemented in Burkina Faso for several years. In view of the insufficient reduction in infant mortality due to multiple factors, strengthening its institutionalisation was recommended in 2019 ...
Hamed Sidwaya Ouedraogo, Hamed Sidwaya Ouedraogo, Ahmed Kabore, Ahmed Kabore, Daouda Ouedraogo, Bètamou Coulibaly, Abdramane Bassiahi Soura, Maxime Koine Drabo, Maxime Koine Drabo   +8 more
doaj   +1 more source

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

BMC Cancer, 2020
Background Effectiveness of L-asparaginase administration in acute lymphoblastic leukemia treatment is mirrored in the overall outcome of patients.
Katerina Hlozkova, Alena Pecinova, Natividad Alquezar-Artieda, David Pajuelo-Reguera, Marketa Simcikova, Lenka Hovorkova, Katerina Rejlova, Marketa Zaliova, Tomas Mracek, Alexandra Kolenova, Jan Stary, Jan Trka, Julia Starkova   +12 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Maternal weight and infections in early childhood: a cohort study. [PDF]

, 2018
OBJECTIVE: The aim of this study was to examine this association between maternal weight during pregnancy and the incidence of hospitalisations for infectious diseases during early childhood. DESIGN: A population-based cohort study.
Videholm, Samuel, Silfverdal, Sven-Arne,, Silfverdal, Sven-Arne, Reniers, Georges, Videholm, Samuel,   +4 more
core   +1 more source

ACTIVATION OF TOLL-LIKE RECEPTORS AND SYNTHESIS OF PROINFLAMMATORY CYTOKINES, CAUSED BY THEVACCINE AGAINST HAEMOPHILUS TYPE B INFECTIONS IN UMBILICAL CORD BLOOD OF NEWBORNS

Медицинский вестник Юга России, 2015
Purpose: to assess the parameters of natural and adaptive immunity to H.influenzae type b in infants to predict the risk of Hib-infection.Materials and methods: examined two groups of infants: I group- born to women with infections during pregnancy (140 ...
A. A. Savisko, M. P. Kostinov, G. G. Harseeva, N. E. Yastrebova, A. D. Shmitko, I. A. Ivanova, A. V. Labushkina, I. V. Podgorniy1   +7 more
doaj   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source