Results 41 to 50 of about 1,616,946 (349)

Childhood trauma and self-stigma in mood disorders [PDF]

, 2023
Childhood maltreatment and mood disorders are associated and linked to self-stigma. In this study, we assessed the relationship between childhood trauma and self-stigma in patients with mood disorders.
Stéphanie Baggio, Anne-Lise Küng, Favre, Sophie, Hofmann, Michel, Hélène Richard-Lepouriel, Alexandre Dayer, Jermann, Françoise, Dayer, Alexandre, Aubry, Jean- Michel, Françoise Jermann, Baggio, Stéphanie, Richard-Lepouriel, Hélène, Sophie Favre, Michel Hofmann, Küng, Anne-Lise, Jean- Michel Aubry   +15 more
core   +1 more source

Childhood trauma and psychopathy in emerging adults: the mediating role of family cohesion

Journal of the Pakistan Medical Association
Objective: To identify the mediating role of family cohesion in the relationship between childhood trauma and psychopathy in Chinese emerging adults.
Jun-Wen Tan, Ying-Ying Li, Hang Li
doaj   +1 more source

Moderating Effect of Resilience between Childhood Trauma and Depression, Rumination in Turkish University Students

Neuropsychiatric Investigation, 2017
Objective: The present study was conducted to see to what extend resilience plays a moderator role between depression, rumination and childhood trauma among university students in Turkey.
Hacer Zeynep Çetinkaya, Gül Alpar, Osman Tolga Arıcak   +2 more
doaj   +1 more source

Intrinsic brain abnormalities in female major depressive disorder patients with childhood trauma: A resting-state functional magnetic resonance imaging study

Frontiers in Neuroscience, 2022
ObjectiveChildhood trauma is a strong predictor of major depressive disorder (MDD). Women are more likely to develop MDD than men. However, the neural basis of female MDD patients with childhood trauma remains unclear.
Juran Chen, Qianyi Luo, Yuhong Li, Zhiyao Wu, Xinyi Lin, Jiazheng Yao, Huiwen Yu, Huiqin Nie, Yingying Du, Hongjun Peng, Huawang Wu   +10 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Prevalence and nature of childhood trauma among patients with schizophrenia and bipolar affective disorder

European Psychiatry, 2023
Introduction Epidemiological studies shows that exposure to early stress in the form of abuse and neglect in childhood increases the risk for later development of severe mental illneses such as schizophrenia and bipolar affective disorder.
A. M. Abdelkarim, T. Molokheya, N. A. Moubark   +2 more
doaj   +1 more source

Emotion regulation mediates the effect of childhood trauma on depression

, 2016
Background Childhood trauma increases the risks of both depression and dysfunctional emotion regulation, which is a factor that has been strongly linked to depression. Because of these demonstrated relationships, it can be hypothesized that dysfunctional
Ebert, David D., Berking, Matthias, Trauma and Grief, Bockting, Claudi, Bockting, C. L. H., Hopfinger, Lisa, Leerstoel Bockting, Bockting, Claudi L.H., Ebert, David D.; id_orcid   +8 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Linking childhood trauma to the psychopathology of schizophrenia: the role of oxytocin

Schizophrenia
Childhood trauma has been linked to schizophrenia, but underlying biological mechanisms remain elusive. This study explored the potential role of plasma oxytocin as a mediator in the relationship between childhood trauma and the psychopathology of ...
Yuan-Jung Chen, Mong-Liang Lu, Yi-Hang Chiu, Chenyi Chen, Vitor Hugo Jesus Santos, Kah Kheng Goh   +5 more
doaj   +1 more source

Rumination as a Mediator between Childhood Trauma and Adulthood Depression/Anxiety in Non-clinical Participants

Frontiers in Psychology, 2017
Objective: Although there is strong evidence that childhood trauma is associated with the development of depression and anxiety, relatively few studies have explored potential mediating factors for this relationship.
Ji S. Kim, Ji S. Kim, Min J. Jin, Min J. Jin, Wookyoung Jung, Sang W. Hahn, Seung-Hwan Lee, Seung-Hwan Lee   +7 more
doaj   +1 more source