Results 51 to 60 of about 1,305,310 (255)

The effects of mood disorders and childhood trauma on fear of positive and negative evaluation

Acta Psychologica, 2022
Fear of positive and negative evaluation is maladaptive and may result in psychosocial dysfunction. Although being diagnosed with mood disorders or experiencing childhood trauma may potentially affect fear of evaluation, previous studies examined this ...
Mora M. Lucero, Skye Satz, Rachel Miceli, Holly A. Swartz, Anna Manelis   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Long Term Effects of Childhood Trauma

, 2022
The first step of throwing clay on a pottery wheel is centering. Centering is fundamental in creating a functional piece, as it ensures even thickness and height throughout the artwork. Without proper centering, the shape of the clay piece will collapse.
Ku, Sydney, Tabatabaei, Deyana, Molchanov, Agatha, Armstrong, Bridget, Storjohann, Kara, George, Caroline   +5 more
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

The Relationship Between Childhood Trauma and Shame: The Mediating Role of Dissociation

European Journal of Investigation in Health, Psychology and Education
Previous research has found significant associations among childhood trauma, dissociation, and shame. Furthermore, the clinical literature suggests that dissociation may foster feelings of shame in individuals who were exposed to childhood trauma.
Gianluca Santoro, Lucia Sideli, Alessandro Musetti, Adriano Schimmenti   +3 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

The impact of childhood sexual abuse on the outcome of intensive trauma-focused treatment for PTSD [PDF]

, 2018
Background: It is assumed that PTSD patients with a history of childhood sexual abuse benefit less from trauma-focused treatment than those without such a history.
Minnen, A. van, Van Minnen, A., De Jongh, A., Anouk Wagenmans, Sleijpen, M., Trauma and Grief, de Jongh, Ad, Wagenmans, A., Marieke Sleijpen, Agnes Van Minnen, Sleijpen, M.J.T., Jongh, A. de, Leerstoel Boelen, Ad De Jongh   +13 more
core   +4 more sources

Childhood trauma and impulsive behaviors: the multiple chain mediating effects of neuroticism, stress perception and depression

BMC Psychology
Background Childhood trauma and impulsive behaviors are frequently observed in clinical pathologies, such as borderline personality disorder and bipolar disorder.
Huihui Yang, Zhaoxia Liu, Zhengmiao Miao, Wanrong Peng, Ming Cheng, Kaili Zheng, Suyao Liu, Qihong Chen, Jinyao Yi   +8 more
doaj   +1 more source

Bridging trauma and eating disorders: the role of loneliness

Frontiers in Psychiatry
IntroductionEating disorders (EDs) are complex and often linked to traumatic childhood experiences. While childhood trauma is known to increase the risk of EDs, the role of loneliness remains underexplored.
Paolo Meneguzzo, Paolo Meneguzzo, Anna Marzotto, Barbara Mezzani, Fabio Conti, Luca Maggi, Patrizia Todisco   +6 more
doaj   +1 more source